Humane endpoints for infectious disease animal models

ILAR Journal

Volumn 41, Issue 2, 2000, Pages 99-104

  Olfert, Ernest D ^a   Godson, Dale L ^b  

^a Animal Resources Centre

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN;

ACUTE PHASE RESPONSE; ANIMAL; ANIMAL WELFARE; CATTLE; COMMUNICABLE DISEASE; COMPARATIVE STUDY; DISEASE MODEL; DOG; EXPERIMENTAL ANIMAL; HORSE; HUMAN; LABORATORY; METHODOLOGY; MICROBIOLOGY; MOUSE; PATHOPHYSIOLOGY; RAT; REVIEW; SPECIES DIFFERENCE; SWINE;

ACUTE-PHASE PROTEINS; ACUTE-PHASE REACTION; ANIMAL WELFARE; ANIMALS; ANIMALS, LABORATORY; CATTLE; COMMUNICABLE DISEASES; DISEASE MODELS, ANIMAL; DOGS; HORSES; HUMANS; LABORATORY ANIMAL SCIENCE; MICE; RATS; SPECIES SPECIFICITY; SWINE;

EID: 0034570573     PISSN: 10842020     EISSN: None     Source Type: Journal    
DOI: 10.1093/ilar.41.2.99     Document Type: Article

References (40)

1. Acred P, Hennessey TD, MacArthur-Clark, JA, Merrikin DJ, Ryan DM, Smulders HC, Troke PF, Wilson RG, Straughan DW. 1994. Guidelines for the welfare of animals in rodent protection tests - A report of the Rodent Protection Test Working Party. Lab Anim 28:13-18.
2. Baumans V, Brain PF, Brugere H, Clausing P, Jeneskog T, Perretta G. 1994. Pain and distress in laboratory rodents and Iagomorphs. Report of the FELASA Working Group on Pain and Distress. Lab Anim 28:97-112.
3. CCAC [Canadian Council on Animal Care]. 1998. CCAC guidelines on: Choosing an appropriate endpoint in experiments using animals for research, teaching, and testing. Canadian Council on Animal Care, Ottawa, Canada.
4. Conner JG, Eckersall PD, Wiseman A, Aitchison TC, Douglas TA. 1988. Bovine acute phase response following turpentine injection. Res Vet Sci 44:82-88.
5. Conner JG, Eckersall PD, Wiseman A, Bain RK, Douglas TA. 1989. Acute phase response in calves following infection with Pasteurella hemolytica, Ostertagia ostertagi, and endotoxin administration. Res Vet Sci 47:203-207.
6. Dray A. 1995. Inflammatory mediators of pain. Br J Anaesth 75:125-131.
7. Eckersall PD. 1992. Meat inspection - The potential of acute phase protein assay. Meat Focus Int, Oct:279-283.
8. Eckersall PD. 1995. Acute phase proteins as markers of inflammatory lesions. Comp Hematol Int 5:93-97.
9. Eckersall PD, Conner JG. 1988. Bovine and canine acute phase proteins. Vet Res Commun 12:169-178.
10. Fenner F, Pastoret P-P, Blancou J, Terre J. 1997. Historical introduction. In: Pastoret P-P, Blancou J, Vannier P, Verschueren C, eds. Veterinary Vaccinology. New York: Elsevier, p 3-19.
11. Flecknell PA. 1994. Refinement of animal use - Assessment and alleviation of pain and distress. Lab Anim 28:222-231.
12. Godson DL, Baca-Estrada ME, Babiuk LA. 1997. Applications of bovine cytokines. In: Schijns VECJ, Horzinek MC, eds. Cytokines in Veterinary Medicine. Wallingford, UK: CAB Int. p 3-13.
13. Godson DL, Baca-Estrada ME, Van Kessel AG, Hughes HPA, Morsey MA, Van Donkersgoed J, Harland RJ, Shuster DE, Daley MJ, Babiuk LA. 1995. Regulation of bovine acute phase responses by recombinant Interleukin-1β. Can J Vet Res 59:249-255.
14. Godson DL, Campos M, Attah-Poku SK, Redmond MJ, Cordeiro DM, Sethi MS, Harland RJ, Babiuk LA. 1996. Serum haptoglobin as an indicator of the acute phase response in bovine respiratory disease. Vet Immunol Immunopathol 51:277-292.
15. Gregory NG. 1998. Physiological mechanisms causing sickness behaviour and suffering in diseased animals. Anim Welf 7:293-305.
16. Hirvonen J, Pyorala S, Jousimies Somer H. 1996. Acute phase response in heifers with experimentally induced mastitis. J Dairy Res 63:351-360.
17. Hofner MC, Fosbery MW, Eckersall PD, Donaldson AI. 1994. Haptoglobin response of cattle infected with foot-and-mouth disease virus. Res Vet Sci 57:125-128.
18. Horadagoda A, Eckersall PD, Hodgson JC, Gibbs HA, Moon GM. 1994. Immediate responses in serum TNFa and acute phase protein concentrations to infection with Pasteurella haemolytica A1 in calves. Res Vet Sci 57:129-132.
19. Kort WJ, Hekking-Weijma JM, TenKate MT, Sorm V, VanStrik R. 1998. A microchip implant system as a method to determine body temperature of terminally ill rats and mice. Lab Anim 32:260-269.
20. Love JA, Booth CD, Boyd J. 1996. Remote temperature sensing for determining humane endpoints. Poster presentation (not included in Proceedings): 2nd World Congress on Alternatives and Animal Use in the Life Sciences. Utrecht, The Netherlands.
21. Makimura S, Suzuki N. 1982. Quantitative determination of bovine serum haptoglobin and its elevation in some disease conditions. Jpn J Vet Sci 44:15-21.
22. McNair J, Elliott CT, Mackie DP. 1995. Development of a sensitive and specific time resolved fluorimetric immunoassay for the bovine acute phase protein haptoglobin (HP). J Immunol Meth 184:199-206.
23. Morimatsu M, Sarikaputi M, Syuto B, Saito M, Yamamoto S, Naiki M. 1992. Bovine haptoglobin: Single radial immunodiffusion assay of its polymeric forms and dramatic rise in acute-phase sera. Vet Immunol Immunopathol 33:365-372.
24. Morton DB. 1990. Adverse effects in animals and their relevance to refining scientific procedures. ATLA 18:29-39.
25. Morton DB. 1997a. A scheme for the recognition and assessment of adverse effects in animals. In: Van Zutphen LFM, Balls M, eds. Animal Alternatives, Welfare and Ethics. Amsterdam: Elsevier Science, p 235-240.
26. Morton DB 1997b. Socio-economic and ethical aspects. Part 4. Ethical and refinement aspects of animal experimentation. In: Pastoret P-P, Blancou J, Vannier P, Verschueren C, editors. Veterinary Vaccinology. New York: Elsevier Science, p 763-785.
27. Morton DB, Townsend P. 1995. Dealing with adverse effects and suffering during animal research. In: Tuffery AA, ed. Laboratory Animals - An Introduction for Experimenters. 2nd ed. Chichester: John Wiley & Sons Ltd. p 215-231.
28. Murata H, Miyamoto T. 1993. Bovine haptoglobin as a possible immunomodulator in the sera of transported calves. Br Vet J 149:277-283.
29. NRC [National Research Council]. 1992. Recognition and Alleviation of Pain and Distress in Laboratory Animals. Washington: National Academy Press. p 32-53.
30. Olfert ED. 1995. Defining an acceptable endpoint in invasive experiments. AWIC Newslett 6(1):3-7.
31. Salonen M, Hirvonen J, Pyorala S, Sankari S, Sandholm M. 1996. Quantitative determination of bovine serum haptoglobin in experimentally induced Escherichia coli mastitis. Res Vet Sci 60:88-91.
32. Schijns VECJ, Horzinek MC. 1997 Introduction. In: Schijns VECJ, Horzinek MC, eds. Cytokines in Veterinary Medicine. Wallingford, UK: CAB Int. p xix-xxiv.
33. Siems JJ, Allen SD. 1989. Early euthanasia as an alternative to death in chronic infectious disease studies using a systemic Candida albicans model. Abstr. 89th Annual Meeting of the American Society for Microbiology.
34. 50 for the measurement of bacterial virulence. Int J Exp Pathol 75:95-98.
35. van Deuren M, Dofferhoff ASM, van der Meer JWM. 1992. Cytokines and the response to infection. J Pathol 168:349-356.
36. Wagner L, Gessl A, Baumgartner Parzer S. 1996. Haptoglobin phenotyping by newly developed monoclonal antibodies. J Immunol 156:1989-1996.
37. Wallace J, Sanford J, Smith MW, Spencer KV. 1990. The assessment and control of the severity of scientific procedures on laboratory animals. Lab Anim 24:97-130.
38. Wolfensohn S, Lloyd M. 1994. Recognition of pain and stress in laboratory animals. In: Handbook of Laboratory Animal Management and Welfare. Oxford, England: Oxford University Press, p 174-180.
39. Wong JP, Saravolac EG, Clement JG, Nagata LP. 1997. Development of a murine hypothermia model for study of respiratory tract influenza virus infection. Lab Anim Sci 47:143-147.
40. Workman P, Twentyman P, Balkwill F, Balmain A, Chaplin D, Double J, Embleton J, Newell D, Raymond R, Stables J, Stephens T, Wallace J. 1998. United Kingdom Coordinating Committee on Cancer Research (UKCCCR) Guidelines for the welfare of animals in experimental neoplasia (2nd ed, July 1997). Br J Cancer 77:1-10.