메뉴 건너뛰기




Volumn 12, Issue 1, 2000, Pages 43-49

Expression of p53 and bcl-2 in clinically localized prostate cancer before and after neo-adjuvant hormonal therapy

Author keywords

bcl 2; Hormonal therapy; Hormone resistance; p53; Prognosis; Prostate cancer

Indexed keywords

ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; DRUG DERIVATIVE; GONADORELIN; PROTEIN BCL 2; PROTEIN P53; TUMOR MARKER;

EID: 0034567449     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000001108747435     Document Type: Article
Times cited : (8)

References (42)
  • 4
    • 0025831844 scopus 로고
    • Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the urinary bladder
    • Wright, C.; Mellon, K.; Johnston, P.; Lane, D. P.; Harris, A. L.; Horne, C. H. W. Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the urinary bladder. Br. J. Cancer 63:967-970; 1991.
    • (1991) Br. J. Cancer , vol.63 , pp. 967-970
    • Wright, C.1    Mellon, K.2    Johnston, P.3    Lane, D.P.4    Harris, A.L.5    Horne, C.H.W.6
  • 6
    • 0027979718 scopus 로고
    • Association of p53 immunoreactivity with high Gleason tumor grade in prostatic adcnocarcinoma
    • Kallakury, B. V. S.; Figge, J.; Ross, J. S.; Fisher, H. A. G.; Figge, H. L.; Jennings, T. A. Association of p53 immunoreactivity with high Gleason tumor grade in prostatic adcnocarcinoma. Hum. Pathol. 25:92-97; 1994.
    • (1994) Hum. Pathol. , vol.25 , pp. 92-97
    • Kallakury, B.V.S.1    Figge, J.2    Ross, J.S.3    Fisher, H.A.G.4    Figge, H.L.5    Jennings, T.A.6
  • 7
    • 0028179999 scopus 로고
    • Immunohistochcmical determination of p53 protein nuclear accumulation in prostatic adenocarcinoma
    • Aprikian, A. G.; Sarkis, A. S.; Fair, W. R.; Zhang, Z-F.; Fuks, Z.; Cordon-Cardo, C. Immunohistochcmical determination of p53 protein nuclear accumulation in prostatic adenocarcinoma. J. Urol. 151:1276-1280; 1994.
    • (1994) J. Urol. , vol.151 , pp. 1276-1280
    • Aprikian, A.G.1    Sarkis, A.S.2    Fair, W.R.3    Zhang, Z.-F.4    Fuks, Z.5    Cordon-Cardo, C.6
  • 8
    • 0026651717 scopus 로고
    • Small subgroup of aggressive, highly proliferative prostatic carcinomas defined by p53 accumulation
    • Visakorpi, T.; Kallioniemi, O. P.; Heikkincn, A.; Koivula, T.; Isola, J. Small subgroup of aggressive, highly proliferative prostatic carcinomas defined by p53 accumulation. J. Natl. Cancer Inst. 84:883-887; 1992.
    • (1992) J. Natl. Cancer Inst. , vol.84 , pp. 883-887
    • Visakorpi, T.1    Kallioniemi, O.P.2    Heikkincn, A.3    Koivula, T.4    Isola, J.5
  • 9
    • 0030070342 scopus 로고    scopus 로고
    • bcl-2: Role in epithelial differentiation and oncogenesis
    • Lu, Q-L.; Abel, P.; Foster, C. S.; Lalani, E-N. bcl-2: Role in epithelial differentiation and oncogenesis. Hum. Pathol. 27:102-110; 1996.
    • (1996) Hum. Pathol. , vol.27 , pp. 102-110
    • Lu, Q.-L.1    Abel, P.2    Foster, C.S.3    Lalani, E.-N.4
  • 11
    • 0029819406 scopus 로고    scopus 로고
    • Protein expression of p53, bcl-2 and KI-67 (MIB-1) as prognostic biomarkers in patients with surgically treated, clinically localized prostate cancer
    • Moul, J. W.; Bettencourt, M-C.; Sesterhenn, I. A.; Mostofi, F. K.; McLeod, D. G.; Srivastava, S.; Bauer, J. J. Protein expression of p53, bcl-2 and KI-67 (MIB-1) as prognostic biomarkers in patients with surgically treated, clinically localized prostate cancer. Surgery 120:159-167; 1996.
    • (1996) Surgery , vol.120 , pp. 159-167
    • Moul, J.W.1    Bettencourt, M.-C.2    Sesterhenn, I.A.3    Mostofi, F.K.4    McLeod, D.G.5    Srivastava, S.6    Bauer, J.J.7
  • 13
    • 0028918150 scopus 로고
    • Androgen ablation-induced programmed death of prostatic glandular cells docs not involve recruitment into a defective cell cycle or p53 induction
    • Furuya, Y.; Lin, X. S.; Walsh, J. C.; Nelson, W. G.; Isaacs, J. T. Androgen ablation-induced programmed death of prostatic glandular cells docs not involve recruitment into a defective cell cycle or p53 induction. Endocrinology 136:1898-1906; 1995.
    • (1995) Endocrinology , vol.136 , pp. 1898-1906
    • Furuya, Y.1    Lin, X.S.2    Walsh, J.C.3    Nelson, W.G.4    Isaacs, J.T.5
  • 14
    • 0031960297 scopus 로고    scopus 로고
    • Growth-inhibitory effects of luteinizing hormone-releasing hormone (LHRH) agonists on xenografts of the du 145 human androgen-independent prostate cancer cell line in nude mice
    • Dondi, D.; Moretti, R. M.; Montagnani Marelli, M.; Pratesi, G.; Polizzi, D.; Milani, M.; Motta, M.; Limonta, P. Growth-inhibitory effects of luteinizing hormone-releasing hormone (LHRH) agonists on xenografts of the DU 145 human androgen-independent prostate cancer cell line in nude mice. Int. J. Cancer 76:506-511; 1998.
    • (1998) Int. J. Cancer , vol.76 , pp. 506-511
    • Dondi, D.1    Moretti, R.M.2    Montagnani Marelli, M.3    Pratesi, G.4    Polizzi, D.5    Milani, M.6    Motta, M.7    Limonta, P.8
  • 15
    • 0030802625 scopus 로고    scopus 로고
    • The prognostic value of pretreatment expression of androgen receptor and bcl-2 in hormonally treated prostate cancer patients
    • Noordzij, M. A.; Bogdanowicz, J. F. A. T.; van Krimpen, C.; van der Kwast, T. H.; van Steenbrugge, G. J. The prognostic value of pretreatment expression of androgen receptor and bcl-2 in hormonally treated prostate cancer patients. J. Urol. 158:1880-1885; 1997.
    • (1997) J. Urol. , vol.158 , pp. 1880-1885
    • Noordzij, M.A.1    Bogdanowicz, J.F.A.T.2    Van Krimpen, C.3    Van Der Kwast, T.H.4    Van Steenbrugge, G.J.5
  • 16
    • 0031965135 scopus 로고    scopus 로고
    • Short-term cellular effects induced by castration therapy in relation to clinical outcome in prostate cancer
    • Stattin, P.; Westin, P.; Damber, J-E.; Bergh, A. Short-term cellular effects induced by castration therapy in relation to clinical outcome in prostate cancer. Br. J. Cancer 77:670-675; 1998.
    • (1998) Br. J. Cancer , vol.77 , pp. 670-675
    • Stattin, P.1    Westin, P.2    Damber, J.-E.3    Bergh, A.4
  • 18
    • 0029130393 scopus 로고
    • TP53 mutations in prostatic cancer. Analysis of pre- and post-treatment archival formalin-fixed tumour tissue
    • Berner, A.; Geitvik, G.; Karlsen, F.; Fossa, S. D.; Nesland, J. M.; Borresen, A. L. TP53 mutations in prostatic cancer. Analysis of pre- and post-treatment archival formalin-fixed tumour tissue. J. Pathol. 176:299-308; 1995.
    • (1995) J. Pathol. , vol.176 , pp. 299-308
    • Berner, A.1    Geitvik, G.2    Karlsen, F.3    Fossa, S.D.4    Nesland, J.M.5    Borresen, A.L.6
  • 19
    • 0032935293 scopus 로고    scopus 로고
    • Amplification of the androgen receptor gene is associated with P53 mutation in hormone-refractory recurrent prostate cancer
    • Koivisto, P. A.; Rantala, I. Amplification of the androgen receptor gene is associated with P53 mutation in hormone-refractory recurrent prostate cancer. J. Pathol. 187:237-241; 1999.
    • (1999) J. Pathol. , vol.187 , pp. 237-241
    • Koivisto, P.A.1    Rantala, I.2
  • 20
    • 0001916430 scopus 로고
    • Histological grading and clinical staging of prostatic carcinoma
    • Tannenbaum, M., ed. Philadelphia: Lea and Febiger
    • Gleason, D. F. The Veteran's Administration Cooperative Urologic Research Group: Histological grading and clinical staging of prostatic carcinoma. In: Tannenbaum, M., ed. Urologic pathology. The prostate. Philadelphia: Lea and Febiger; 1977:171-198.
    • (1977) Urologic Pathology. The Prostate , pp. 171-198
    • Gleason, D.F.1
  • 21
    • 0026077630 scopus 로고
    • Pathologic changes associated with androgen deprivation therapy for prostate cancer
    • Murphy, W. M.; Soloway, M. S.; Barrows, G. H. Pathologic changes associated with androgen deprivation therapy for prostate cancer. Cancer 68:821-828; 1991.
    • (1991) Cancer , vol.68 , pp. 821-828
    • Murphy, W.M.1    Soloway, M.S.2    Barrows, G.H.3
  • 22
    • 0025970529 scopus 로고
    • Effect of combination endocrine therapy (LHRH agonist and flutamide) on normal prostate and prostatic adenocarcinoma. A histopathologic and immunohistochemical study
    • Tetu, B.; Srigley, J. R.; Boivin, J.; Dupont, A.; Monfette, G.; Pinault, S.; Labrie, F. Effect of combination endocrine therapy (LHRH agonist and flutamide) on normal prostate and prostatic adenocarcinoma. A histopathologic and immunohistochemical study. Am. J. Surg,. Pathol. 15:111-120; 1991.
    • (1991) Am. J. Surg,. Pathol. , vol.15 , pp. 111-120
    • Tetu, B.1    Srigley, J.R.2    Boivin, J.3    Dupont, A.4    Monfette, G.5    Pinault, S.6    Labrie, F.7
  • 23
    • 0028209957 scopus 로고
    • Histologic changes in prostate carcinoma treated with leuprolide (luteinizing hormone-releasing hormone effect). Distinction from poor tumor differentation
    • Smith, D. M.; Murphy, W. M. Histologic changes in prostate carcinoma treated with leuprolide (luteinizing hormone-releasing hormone effect). Distinction from poor tumor differentation. Cancer 73:1472-1477; 1994.
    • (1994) Cancer , vol.73 , pp. 1472-1477
    • Smith, D.M.1    Murphy, W.M.2
  • 24
    • 6844238724 scopus 로고
    • Quantitative investigation of cell loss in prostate carcinomas: Clinical-morphological aspects
    • Stiens, R.; Helpap, B.; Weissbach, L. Quantitative investigation of cell loss in prostate carcinomas: Clinical-morphological aspects. Verh. Ges. Urol. 32:73-74; 1981.
    • (1981) Verh. Ges. Urol. , vol.32 , pp. 73-74
    • Stiens, R.1    Helpap, B.2    Weissbach, L.3
  • 25
    • 0031975628 scopus 로고    scopus 로고
    • Androgen receptor gene and hormonal therapy failure of prostate cancer
    • Koivisto, P.; Kolmer, M.; Visakorpi, T.; Kallioniemi, O-P. Androgen receptor gene and hormonal therapy failure of prostate cancer. Am. J. Pathol. 152:1-9; 1998.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1-9
    • Koivisto, P.1    Kolmer, M.2    Visakorpi, T.3    Kallioniemi, O.-P.4
  • 27
    • 0028817084 scopus 로고
    • Immunohistochemical detection of p53 protein as a prognostic indicator in prostate cancer
    • Shurbaji, M. S.; Kalbfleisch, J. H.; Thurmond, T. S. Immunohistochemical detection of p53 protein as a prognostic indicator in prostate cancer. Hum. Pathol. 26:106-109; 1995.
    • (1995) Hum. Pathol. , vol.26 , pp. 106-109
    • Shurbaji, M.S.1    Kalbfleisch, J.H.2    Thurmond, T.S.3
  • 28
    • 0030967596 scopus 로고    scopus 로고
    • p53, bcl-2 and retinoblastoma proteins as long-term prognostic markers in localized carcinoma of the prostate
    • Theodorescu, D.; Broder, S. R.; Boyd, J. C.; Mills, S. E.; Frierson, H. F., Jr. p53, bcl-2 and retinoblastoma proteins as long-term prognostic markers in localized carcinoma of the prostate. J. Urol. 158:131-137; 1997.
    • (1997) J. Urol. , vol.158 , pp. 131-137
    • Theodorescu, D.1    Broder, S.R.2    Boyd, J.C.3    Mills, S.E.4    Frierson Jr., H.F.5
  • 30
    • 0031689226 scopus 로고    scopus 로고
    • Ki67 labeling index in core needle biopsies independently predicts tumor-specific survival in prostate cancer
    • Bubendorf, L.; Tapia, C.; Gasser, T. C.; Casella, R.; Grunder, B.; Moch, H.; Mihatsch, M. J.; Sauter, G. Ki67 labeling index in core needle biopsies independently predicts tumor-specific survival in prostate cancer. Hum. Pathol. 29:949-954; 1998.
    • (1998) Hum. Pathol. , vol.29 , pp. 949-954
    • Bubendorf, L.1    Tapia, C.2    Gasser, T.C.3    Casella, R.4    Grunder, B.5    Moch, H.6    Mihatsch, M.J.7    Sauter, G.8
  • 31
    • 0032853502 scopus 로고    scopus 로고
    • Preoperative p53, bcl-2, CD44 and E-cadherin immunohistochemistry as predictors of biochemical relapse after radical prostatectomy
    • Brewsler, S. F.; Oxley, J. D.; Trivella, M.; Abbott, C,. D.; Gillatt, D. A. Preoperative p53, bcl-2, CD44 and E-cadherin immunohistochemistry as predictors of biochemical relapse after radical prostatectomy. J. Urol. 161:1238-1243; 1999.
    • (1999) J. Urol. , vol.161 , pp. 1238-1243
    • Brewsler, S.F.1    Oxley, J.D.2    Trivella, M.3    Abbott, C.D.4    Gillatt, D.A.5
  • 35
    • 0032927729 scopus 로고    scopus 로고
    • Proliferation- and apoptosis-associated factors in advanced prostatic carcinomas before and after androgen deprivation therapy: Prognostic significance of p21/WAF1/CIP1 expression
    • Baretton, G. B.; Klenk, U.; Diebold, J.; Schmeller, N.; Lohrs, U. Proliferation- and apoptosis-associated factors in advanced prostatic carcinomas before and after androgen deprivation therapy: Prognostic significance of p21/WAF1/CIP1 expression. Br. J. Cancer 80:546-555; 1999.
    • (1999) Br. J. Cancer , vol.80 , pp. 546-555
    • Baretton, G.B.1    Klenk, U.2    Diebold, J.3    Schmeller, N.4    Lohrs, U.5
  • 36
    • 0032892199 scopus 로고    scopus 로고
    • Angiogenesis, p53, bcl-2 and Ki-67 in the progression of prostate cancer after radical prostatectomy
    • Moul, J. W. Angiogenesis, p53, bcl-2 and Ki-67 in the progression of prostate cancer after radical prostatectomy. Eur. Urol. 35:399-407; 1999.
    • (1999) Eur. Urol. , vol.35 , pp. 399-407
    • Moul, J.W.1
  • 37
    • 0031914109 scopus 로고    scopus 로고
    • Heterogeneous expression of E-cadherin and p53 in prostate cancer: Clinical implications
    • BIOMED-II Markers for Prostate Cancer Study Group.
    • Ruijter, E.; van-de-Kaa, C.; Aalders, T.; Ruiter, D.; Miller, G.; Debruyne, F.; Schalken, J. Heterogeneous expression of E-cadherin and p53 in prostate cancer: Clinical implications. BIOMED-II Markers for Prostate Cancer Study Group. Mod. Pathol. 11: 276-281; 1998.
    • (1998) Mod. Pathol. , vol.11 , pp. 276-281
    • Ruijter, E.1    Van-de-Kaa, C.2    Aalders, T.3    Ruiter, D.4    Miller, G.5    Debruyne, F.6    Schalken, J.7
  • 38
    • 0031667532 scopus 로고    scopus 로고
    • Bcl-2 oncoprotein positivity and high MIB-1 (Ki-67) proliferative rate are independent predictive markers for recurrence in prostate carcinoma
    • Keshgegian, A. A.; Johnston, E.; Cnaan, A. Bcl-2 oncoprotein positivity and high MIB-1 (Ki-67) proliferative rate are independent predictive markers for recurrence in prostate carcinoma. Am. J. Clin. Pathol. 110:443-449; 1998.
    • (1998) Am. J. Clin. Pathol. , vol.110 , pp. 443-449
    • Keshgegian, A.A.1    Johnston, E.2    Cnaan, A.3
  • 39
    • 0027093255 scopus 로고
    • Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
    • McDonnell, T. J.; Troncoso, P.; Brisbay, S. M.; Logothetis, C.; Chung, L. W. K.; Hsieh, J-T.; Tu, S-M.; Campbell, M. L. Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res. 52:6940-6944; 1992.
    • (1992) Cancer Res. , vol.52 , pp. 6940-6944
    • McDonnell, T.J.1    Troncoso, P.2    Brisbay, S.M.3    Logothetis, C.4    Chung, L.W.K.5    Hsieh, J.-T.6    Tu, S.-M.7    Campbell, M.L.8
  • 40
    • 0029060164 scopus 로고
    • Castration therapy rapidly induces apoptosis in a minority and decreases cell proliferation in a majority of human prostatic tumors
    • Westin, P.; Stattin, P.; Damber, J-E.; Bergh, A. Castration therapy rapidly induces apoptosis in a minority and decreases cell proliferation in a majority of human prostatic tumors. Am. J. Pathol. 146: 1368-1375; 1995.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1368-1375
    • Westin, P.1    Stattin, P.2    Damber, J.-E.3    Bergh, A.4
  • 41
    • 0032526595 scopus 로고    scopus 로고
    • Apoptosis and related genes in the rat ventral prostate following androgen ablation in response to ethane dimethanesulfonate
    • Woolveridge, I.; Taylor, M. F.; Wu, F. C. W.; Morris, I. D. Apoptosis and related genes in the rat ventral prostate following androgen ablation in response to ethane dimethanesulfonate. Prostate 36:23-30; 1998.
    • (1998) Prostate , vol.36 , pp. 23-30
    • Woolveridge, I.1    Taylor, M.F.2    Wu, F.C.W.3    Morris, I.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.