Visualization of antigen-specific T cell activation in vivo in response to intracerebral administration of a xenopeptide

Experimental Neurology

Volumn 164, Issue 2, 2000, Pages 362-370

  Ni, Hsiao Tzu ^a   Merica, Rebecca R ^b   Spellman, Stephen R ^a   Wang, Jue Mei ^a   Low, Walter C ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Adoptive transfer; CNS antigen; Neural xenotransplantation

Indexed keywords

ANTIGEN; CD4 ANTIGEN; INTERLEUKIN 2; PEPTIDE;

ADOPTIVE TRANSFER; ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; CELL COUNT; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; GRAFT REJECTION; IMMUNE RESPONSE; IMMUNE SYSTEM; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE; XENOGRAFT; XENOTRANSPLANTATION;

EID: 0034537443     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2000.7435     Document Type: Article

References (47)

1. Xenogeneic transplantation
2. Immunologically privileged sites
3. Factors influencing exit of substances from cerebrospinal fluid into deep cervical lymph of the rabbit
4. Allografts of CNS tissue possess a blood-brain barrier: III Neuropathological, methodological, and immunological considerations
5. Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons
6. Kinetic differences in unresponsiveness of thymus and bone marrow cells
7. Drainage of brain extracellular fluid into blood and deep cervical lymph and its immunological significance
8. The role of the regional lymph node in the response to secondarily vascularized grafts
9. Effectiveness of lipid and lipidophilic substances as adjuvants
10. Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen
11. Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation
12. Xenografting of fetal mouse hippocampal tissue to the brain of adult rats: Effects of cyclosporin A treatment
13. Phagocytesis of the antigen, a crucial step in the induction of the primary response
14. Role of regional lymphatics in tumor allograft rejection
15. Role of cervical lymph nodes in the systemic humored immune response to human serum albumin microinfused into rat cerebrospinal fluid
16. Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissue of rat heart and other tissues, but not brain
17. Functional capacity of solid tissue transplants in the brain: Evidence for immunological privilege
18. Human neural graft function in rats treated with anti-interleukin II receptor antibody
19. Cyclosporin A enhances the survivability of mouse cerebral cortex grafted into the third ventricle of rat brain
20. Benefits and risks of hosting animal cells in the human brain
21. The immune system evolved to disriminate infectious nonself from noninfectious self
22. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
23. A natural immunological adjuvant enhances T cell cloned expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism
24. CSF drains directly from the subarachnoid space into nasal lymphatics in the rat Anatomy, histology and immunological significance
25. Molecular bases of the immune response to neural antigens
26. Long-term survival of hamster islet xenografts in mice under short-course treatment with nondepleting versus depleting anti-CD4 monoclonal antibodies
27. Specific suppression of major histocompatibility complex class I and class II genes in astrocytes by brain-enriched gangliosides
28. The anatomy of T-cell activation and tolerance
29. Xenogeneic proliferation and lymphokines production are dependent on CD4 T-cells and self antigen presenting cells in the mouse
30. lo thymocytes in vivo
31. Immunological reaction and blood-brain barrier in mouse-to-rat cross-species neural graft
32. Prevention of neural allograft rejection in the mouse following in vivo depletion of L3T4+ but not Lyt2+ T lymphocytes
33. Neural xenotransplantation: Reconstruction of neuronal circuitry across species barriers
34. + T cells persist in vivo following induction of peripheral tolerance
35. + T cells
36. The effect of a new immunosuppressive agent FK-506, on xenogeneic neural transplantation in rodents
37. + T cells-depleted mice
38. Widespread and selective induction of major histocompatibility complex-determined antigens in vivo by interferon
39. Drainage of interstitial fluid from different regions of rat brain
40. + or B lymphocytes, can reject xenogeneic skin grafts
41. Pathways of fluid drainage from the brain - Morphological aspects and immunological significance in rat and man
42. Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis
43. Interferon-g induces the expression of H-2 and Ia antigens on brain cells
44. A monoclonal antibody to the interleukin-2 receptor enhances the survival of neural allografts: A time-course study
45. Indefinite survival of neural xenografts induced with anti-CD4 monoclonal antibodies
46. Albumin outflow into deep cervical lymph from different regions of rabbit brain
47. The drainage of cerebrospinal fluid into the lymphatic system of the neck in humans