Evaluation of safety of oral vitamin 'A' megadose co-administered with measles vaccination

Indian Pediatrics

Volumn 37, Issue 12, 2000, Pages 1341-1347

  Arya, Sugandha ^b   Chellani, Harish ^a   Pandey, Jyotsna ^a  

^a SAFDARJUNG HOSPITAL   (India)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MEASLES VACCINE; RETINOL;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION FUNCTION; DOUBLE BLIND PROCEDURE; DRUG MEGADOSE; DRUG SAFETY; FEVER; HUMAN; INFANT; INFANTILE DIARRHEA; IRRITABILITY; MAJOR CLINICAL STUDY; MEASLES; MEASLES VACCINATION; NORMAL HUMAN; PREVALENCE; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL; VOMITING;

DOUBLE-BLIND METHOD; GASTROINTESTINAL DISEASES; HEALTH PLANNING; HUMANS; INCIDENCE; INDIA; INFANT; LINEAR MODELS; MEASLES VACCINE; VITAMIN A; VITAMIN A DEFICIENCY;

EID: 0034536807     PISSN: 00196061     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Sommer A. Incidence, prevalence and scale of blinding malnutrition. Lancet 1981; 1: 1407-1408.
2. Sommer A. Vitamin A deficiency and mortality. Lancet, 1992; 339: 864.
3. National Nutrition Monitoring Bureau, Report of Repeat Surveys (1989-90). Hyderabad, National Institute of Nutrition, 1991.
4. Beaton GH, Marorell R, Aronson KJ. Effectiveness of Vitamin A supplementation in the control of young child morbidity and mortality in developing countries. Geneva ACC/SCN, 1992. ACC/SCN State-of-the-Art Series. Nutrition Policy Discussion Paper No. 13, 1992.
5. FAO/WHO. World Declaration and Plan of Action for Nutrition. Rome, December 1992, Geneva. World Health Organization, 1992.
6. Sommer A, Tarwotjo I, Dijunedi E, West KP, Loeden AA, Tilden R, et al. Impact of vitamin A supplementation on childhood mortality. Lancet 1986; 1: 1169-1173.
7. Vitamin A Supplements: A Guide to Their Use in the Treatment and Prevention of Vitamin A Deficiency and Xerophthalmia. WHO/UNICEF/IVACG Task Force, Geneva, 1988.
8. Control of Vitamin A Deficiency, Child Survival and Safe Motherhood Program, Government of India, New Delhi, 1991.
9. Baqui AH, Francisco A de, Arifeen Se, Siddique AK, Sack RB. Bulging fontanelle after supplementation with 25,000 IU of Vitamin A in infancy using immunization contacts. Acta Pediatr 1995; 84: 863-866.
10. Fransciso A de, Chakraborty J, Chowdhary HR, Yunur M, Baqui AH, Siddique AK, et al. Acute toxicity of Vitamin A given with vaccines in infancy. Lancet 1993; 342: 526-527.
11. West KP, Khatry SK, Leclarq SC, Adhikari R, Sec L, Katz J, et al. Tolerance of young infants to a single, large dose of Vitamin A: A randomized community trial in Nepal. Bull WHO, 1992; 70: 733-739.
12. Agoestina T, Humphrey JH, Taylor GA, Usman A, Subardja D, Hadayat S, et al. Safety of one 52 μmol (50,000 IU) oral dose of Vitamin A administered to neonates. Bull WHO, 1994; 72: 859-868.
13. Gomber S, Chellani H. Acute toxicity of vitamin A administered with measles vaccine. Indian Pediatr 1996; 33: 1053-1055.
14. Paterson JCS, Wiggins, HS Serum retinol estimation by spectrophotometric method. J Clin Path 1954; 7: 56-58.
15. Florentino RF, Celste CT, Adelisa CR, Teresa AM, Erlinda PN, Juamina BM, et al. Tolerance of preschoolers to two dosage strength of Vitamin A preparation. Am J Clin Nutr, 1990; 52: 694-700.
16. WHO/CHD immunization linked vitamin A supplementation study group. Randomized trial to assess benefits and safety of vitamin A supplementation linked to immunization in early infancy. Lancet 1998; 352: 1257-1263.
17. National Programme for Control of Blindness, India. Report of National Workshop, New Delhi, Directorate General of Health Services, 1989.
18. Report on Status of Vitamin A Deficiency Programme by Deputy Commissioner Maternal and Child Health, Ministry of Health and Family Welfare, 1995-97, Survey 1998.