An assay to quantify the two plasma isoforms of factor V

Thrombosis and Haemostasis

Volumn 84, Issue 6, 2000, Pages 1066-1071

  Hoekema, L ^a   Rosing, J ^a   Tans, G ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Blood coagulation; Factor V; Thrombosis

Indexed keywords

AMINO ACID; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5A; ISOPROTEIN; PHOSPHATIDYLSERINE; THROMBIN;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; BLOOD ANALYSIS; BLOOD CLOTTING; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); DISEASE ASSOCIATION; ENZYME ACTIVITY; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; QUANTITATIVE DIAGNOSIS; RISK FACTOR; THROMBOCYTE ACTIVATION; THROMBOSIS;

EID: 0034536783     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1614172     Document Type: Article

References (22)

1. Coagulation factor V: An old star shines again
2. Procoagulant and anticoagulant properties of coagulation factor V: Factor V Leiden (APC resistance) causes hypercoagulability by dual mechanisms
3. Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa
4. Influence of Factor V and Factor Va on APC-Induced Cleavage of Human Factor VIII
5. Comparison of activated protein C/protein S-mediated inactivation of human factor VIII and factor V
6. Characterization of two forms of human factor Va with different cofactor activities
7. Partial glycosylation at asparagine-2181 of the second C-type domain of human factor V modulates assembly of the prothrombinase complex
8. Partial glycosylation of Asn2181 in human factor V as a cause of molecular and functional heterogeneity. Modulation of glycosylation efficiency by mutagenesis of the consensus sequence for N-linked glycosylation
9. Human Factor Va1 and Factor Va2: Properties in the Procoagulant and Anticoagulant Pathways
10. Factor V enhances the cofactor function of protein S in the APC-mediated inactivation of factor VIII: Influence of the Factor VR506Q mutation
11. Mutations in the R2-FV gene affect the ratio between the FV isoforms in plasma
12. A factor V genetic component differing from factor V R506Q contributes to the activated protein C resistance phenotype
13. The Factor V gene A4070G mutation and the risk of venous thrombosis
14. Coinheritance of the HR2 haplotype in the Factor V gene confers an increased risk of venous thromboembolism to carriers of Factor V R506Q (factor V Leiden)
15. Factor V gene mutations (R2 gene) are associated with coronary artery disease in elderly people
16. Characterization of protein S, a gamma-carboxy-glutamic acid containing protein from bovine and human plasma
17. The rate-determining step of the heparin-catalyzed antithrombin/thrombin reaction is independent of thrombin
18. Isolation of human blood coagulation alpha-factor Xa by soybean trypsin inhibitor-sepharose chromatography and its active-site titration with fluorescein mono-p-guanidinobenzoate
19. A rapid and sensitive sub-micro phosphorus determination
20. The role of phospholipids and factor Va in the prothrombinase complex
21. Radioimmunoassay of factor V in human plasma and platelets
22. Meizothrombin formation during factor Xa-catalyzed prothrombin activation. Formation in a purified system and in plasma