Quantitation by 1H-NMR of dolichol, cholesterol and choline-containing lipids in extracts of normal and phathological thyroid tissue

NMR in Biomedicine

Volumn 13, Issue 7, 2000, Pages 377-383

  Yoshioka, Yoshichika ^a   Sasaki, Jun ^a   Yamamoto, Masahide ^a   Saitoh, Kazuyoshi ^a   Nakaya, Shigeyuki ^a   Kubokawa, Manabu ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Basedow disease; Cholesterol; Dolichol; Isoprenoids; Magnetic resonance spectroscopy; Papillary cancer; Phospholipids; Thyroid gland

Indexed keywords

CHOLESTEROL; CHOLINE; DOLICHOL; ISOPRENOID; LYSOSOME ENZYME; PHOSPHOLIPID; THYROID HORMONE; TISSUE EXTRACT; UNSATURATED FATTY ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GRAVES DISEASE; HORMONE SYNTHESIS; HUMAN; HUMAN TISSUE; LYSOSOME; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ASSAY; THYROID ADENOMA; THYROID GLAND; THYROID PAPILLARY CARCINOMA; THYROTROPIN RELEASE; TISSUE LEVEL;

CARCINOMA, PAPILLARY; CHOLESTEROL; CHOLINE; DOLICHOL; GRAVES DISEASE; HUMANS; LIPID METABOLISM; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; THYROID GLAND; THYROID NEOPLASMS; TISSUE EXTRACTS;

EID: 0034535744     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1492(200011)13:7<377::AID-NBM658>3.0.CO;2-E     Document Type: Article

References (38)

1. Dolichol: A curriculum cognitionis
2. The importance of being dolichol
3. Glyceraldehyde 3-phosphate and pyruvate as precursors of isoprenic units in an alternative non-mevalonate pathway for terpenoid biosynthesis
4. The biological role of dolichol
5. Dolichol: Function, metabolism, and accumulation in human tissues
6. High levels of brain dolichols in neuronal ceroid-lipofuscinosis and senescence
7. Dolichol monophosphate glucose: An intermediate in glucose transfer in liver
8. Effects of growth factors on cell cycle arrest in dolichyl phosphate-depleted cultures
9. The Escherichia coli homologue of yeast RER2, a key enzyme of dolichol synthesis, is essential for carrier lipid formation in bacterial cell wall synthesis
10. Dolichyl phosphate, a potent inducer of apoptosis in rat glioma C6 cells
11. Control of N-linked carbohydrate unit synthesis in Thyroid endoplasmic reticulum by membrane organization and dolichyl phosphate availability
12. Autoimmune thyroid disease: Further developments in our understanding
13. Determination of unsaturation and average molecular weight of natural fats by nuclear magnetic resonance
14. 1H NMR
15. A simple method for the isolation and purification of total lipids from animal tissues
16. 31P-magnetic resonance spectroscopic analysis
17. The subcellular localization of enzymes of dolichol metabolism in rat liver
18. The site of biosynthesis and intracellular deposition of dolichol in rat liver
19. Variations in the structure of thyroglohulins from normal and goitrous human thyroids
20. Structural changes of carbohydrate chains of human thyroglobulin accompanying malignant transformations of thyroid glands
21. Occurrence of dolichol in human tissues
22. Dolichol and dolichyl phosphate in human tissues
23. Separation, quantitation and distribution of dolichol and dolichyl phosphate in rat and human tissues
24. Role of dolichyl phosphate in regulation of protein glycosylation in 2-acetylamino-fluorene-induced carcinogenesis in rat liver
25. Dolichol biosynthesis in human malignant cells
26. Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways
27. Loss of feedback control of hydroxymethylglutaryl coenzyme A reductase in hepatomas
28. A discoordinate increase in the cellular amount of 3-hydroxy-3-methylglutaryl-CoA reductase results in the loss of rate-limiting control over cholesterogenesis in a tumor cell-free system
29. 1H nuclear magnetic resonance spectroscopy of tissue extracts and discriminant factor analysis
30. In vitro NMR evaluation of human thyroid lesions
31. Proton magnetic resonance and human thyroid neoplasia. I: Discrimination between benign and malignant neoplasms
32. Influence of dolichol on microsomal membrane functions
33. Thyrotropin controls dolichol-linked sugar pools and oligosaccharyltransferase activity in thyroid cells
34. Physiological variations in thyroid hormones: Physiological and pathophysiological considerations
35. Fine structural changes in the aging mouse thyroid
36. Lipid-rich residual bodies in the human thyroid gland: Ultrastructural, histochemical, and morphometric study
37. Age-dependent accumulation of dolichol in rat liver: Is tissue dolichol a biomarker of aging?
38. Enzymatic formation of dehydrodolichal and dolichal, new products related to yeast dolichol biosynthesis