Pregnancy and benzodiazepines;Benzodiazépines et grossesse

Therapie

Volumn 55, Issue 5, 2000, Pages 587-595

  Perault, M C ^a   Favreliere, S ^a   Minet, Ph ^b   Remblier, C ^a  

^a POITIERS UNIVERSITY HOSPITAL   (France)

^b Service Diététique   (France)

Author keywords

Animal; Benzodiazepine; Cleft lip; Cleft palate; Floppy infant; Human; Pregnancy

Indexed keywords

ALPRAZOLAM; ANXYREX; BENZODIAZEPINE DERIVATIVE; BROMAZEPAM; CLOBAZAM; CLONAZEPAM; CLORAZEPATE DIPOTASSIUM; CLOTIAZEPAM; DIAZEPAM; EQUITAM; ESTAZOLAM; ETHYL LOFLAZEPATE; FLUNITRAZEPAM; LOPRAZOLAM; LOPRAZOLAM MESILATE; LORAZEPAM; LORMETAZEPAM; NITRAZEPAM; NOCTAMIDE; NORDAZEPAM; NOVASAM; OXAZEPAM; PRAZEPAM; TEMAZEPAM; TRANDOLAPRIL PLUS VERAPAMIL; TRIAZOLAM; UNCLASSIFIED DRUG;

CLEFT LIP; CLEFT PALATE; DRUG SAFETY; FAILURE TO THRIVE; FETOTOXICITY; FETUS MALFORMATION; HUMAN; INFANTILE HYPOTONIA; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SELF MEDICATION; TERATOGENICITY; WITHDRAWAL SYNDROME;

ABNORMALITIES, DRUG-INDUCED; ADULT; ANIMALS; ANTI-ANXIETY AGENTS; ANTICONVULSANTS; BENZODIAZEPINES; CLEFT LIP; CLEFT PALATE; CLINICAL TRIALS; CRICETINAE; DRUG EVALUATION, PRECLINICAL; FEMALE; FRANCE; HERNIA, INGUINAL; HUMANS; INFANT, NEWBORN; MATERNAL-FETAL EXCHANGE; MICE; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES; RABBITS; RATS; REGISTRIES; SELF MEDICATION; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0034535562     PISSN: 00405957     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (69)

1. Perinatal benzodiazepine modulation of GABA(A) receptor function: Influence on adaptative responses
2. The effect of benzodiazepines on the fetus and the newborn
3. Effects of oral administration of alprazolam on rabbit fetus
4. Effects of oral administration of alprazolam on the rat fetus. Experiment on drug administration during the organogenesis period
5. Does prenatal alprazolam exposure increase anxiety in adult mice offspring?
6. Reproduction study on suppository of bromazepam (KL-001). Teratology study in rats and rabbits
7. Reproductive studies of clobazam in the rat and rabbit
8. Fetal toxicity of benzodiazepines in rats
9. Comparative teratogenicity of six antiepileptic drugs in the mouse
10. Prenatal benzodiazepine immunosuppression: Possible involvement of peripheral benzodiazepine site
11. Studies on the toxicity of clonazepam? Teratogenicity tests in rabbits
12. Pharmacological, toxicological and teratological studies on dipotassium-tchloro-3-carboxy-1,3-dihydro-2,2-dihydroxy-5-phenyl-2H-1,4-benzo diazepine-chlorazepate (Dipotassium Chlorazepate, 4306CB)
13. Failure of chlomzepate to cause malformations or feral wastage in the rat
14. Delayed mazelearning in rats after prenatal exposure to clorazepate
15. The teratogenicity of diazepam metabolites in Swiss-Webster mice
16. Teratogenicity of oral diazepam and diphenylhydantoin in mice
17. Studies on the embryotoxic risk of drug treatment during the preimplantation period in the mouse
18. Study of the teratogenic potential of diazepam and SCH 12041
19. Prenatal exposure to diazepam alters behavior development in rats
20. Behavior consequences of prenatal diazepam exposure in rats
21. Prenatal exposure to diazepam alters central and peripheral responses to stress in adult rat offspring
22. Diazepam effects on the fetus
23. Teratogenic effects of diazepam in the hamster
24. Teratological and reproduction studies with a new hypuotic, 5-(2-fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1, 4-diazepine-2-one (flunitrazepam)
25. The effect of flunitrazepam on reproduction in the rat. The use of cross-fostering in the evaluation of postnatal parameters in rat reproduction studies
26. Cleft palate and open eyelids inducing activity of lorazepam and the effect of flumazenil, the benzodiazepine antagonist
27. Prenatal exposure to benzodiazepine 1: Prenatal exposure to lorazepam in mice alters open-field activity and GABA A receptor function
28. Teratogenicity of lorazepam (WY-4036) in mice and rats
29. Teratogenic effects of nitrazepam in rats
30. Prenatal benzodiazepine effects in mice. Post natal behavioral development, response to drug challenges, and adult discrimination learning
31. Short-, medium-, and long-term effects of prenatal oxazepam on neurobehavioral development of mice
32. Toxicity of some benzodiazepine compounds with CNS activity
33. Safety studies of prazepam (K-373). Teratological study in rats
34. Safety studies of prazepam (K-373). Teratological study in rabbits
35. Reproduction studies of triazolam in rats and rabbits
36. Association between cleft lip with or without cleft palate and prenatal exposure to diazepam
37. Exposure to prescribed drugs in pregnancy and association with congenital malformations
38. Epidemiology of cleft lip and palate. An attempt to rule out chance correlations
39. Associations between oral clefts and drugs taken dining pregnancy
40. Exogenous hormones and other drugs: Exposures of children with congenital heart disease
41. Congenital heart disease in relation to maternal use of Bendectin and other drugs in early pregnancy
42. Lack of relation of oral clefts to diazepam use during pregnancy
43. Congenital heart disease in the offspring and maternal habits and home exposures during pregnancy
44. Lack of evidence of teratogenicity of benzodiazepine drugs in Hungary
45. Evaluation of anticonvulsivant drugs during pregnancy in a population-based Hungarian study
46. Benzodiazepines in pregnancy: Analysis of 187 exposed infants drawn from a population-based birth detects registry
47. Neurodevelopment in late infancy after prenatal exposure to benzodiazepines - A prospective study
48. Is benzodiazepine use during pregnancy really teratogenic?
49. Effects of exposure to benzodiazepine during fetal life
50. Withdrawal symptoms in neonates from intrauterine exposure to diazepam
51. Teratogenic effects of benzodiazepine use during pregnancy
52. First-trimester drug use and congenital disorders
53. Pregnancy outcome in women exposed to non-Valium benzodiazepines
54. First-trimester exposure to alprazolam
55. Alprazolam exposure during early human pregnancy
56. Effect of maternal lorazepam on the neonate
57. Neonatal apnea associated with maternal donazepam therapy: A case report
58. Clorazepate and congenital malformations
59. Acentric craniofacial cleft in a newborn female prenatally exposed to a high dose of diazepam
60. Floppy-infant syndrome and maternal diazepam and/or nitrazepam
61. Developmental, neuro and immunotoxic effects of perinatal diazepam treatment in rats
62. Prenatal stress induces body weight deficit and behavioural alterations in rats: The effect of diazepam
63. Effect of benzodiazepines in neonates
64. Effects of diazepam on uteroplacental and foetal hemodynamics and metabolism
65. Effect of diazepam on uterine activity during labor
66. Diazepam in preeclamptic toxoemia with special reference to its effect on the newborn infant
67. Benzodiazepine use in pregnancy and major malformations or oral clefts: Meta-analysis of cohort and case control studies
68. Benzodiazepine use in pregnancy and major malformations or oral clefts
69. Effets chez le nouveau-né des benzodiazépines administrées a la mére