Induction of enlarged intestinal lymphoid aggregates during acute glutathione depletion in a murine model

Digestive Diseases and Sciences

Volumn 45, Issue 11, 2000, Pages 2115-2121

  Koch, T R ^a,b,c   Yuan, L X ^a,b,c   Fink, J G ^a,b,c   Petro, A ^a,b,c   Opara, E C ^a,b,c  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Animal; Disease models; Glutathione; Intestines; Lymphoid tissue

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BUTHIONINE SULFOXIMINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE ETHYL ESTER; LIPID PEROXIDE; NEUROHORMONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON; CONTROLLED STUDY; ENTERITIS; ENZYME INHIBITION; GERMINAL CENTER; HISTOLOGY; ILEUM; INFLAMMATION; INTESTINE LYMPHATIC TISSUE; INTESTINE MUCOSA; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SUBMUCOSA;

ANIMALS; DISEASE MODELS, ANIMAL; GLUTATHIONE; HYPERTROPHY; INFLAMMATORY BOWEL DISEASES; LYMPHOID TISSUE; MICE; MICE, INBRED A; OXIDATIVE STRESS;

EID: 0034534498     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026423420759     Document Type: Article

References (30)

1. Cellular defenses against damage from reactive oxygen species
2. Glutathione is required for intestinal function
3. Glutathione-ascorbic acid antioxidant system in animals
4. Glutathione deficiency in human disease
5. Colonic mucosal antioxidant enzymes and lipid peroxide levels in normal subjects and patients with ulcerative colitis
6. Decrease in two intestinal Cu/Zn containing proteins with antioxidant function in inflammatory bowel disease
7. Altered ascorbic acid status in the mucosa from inflammatory bowel disease patients
8. Glutathione metabolism in Crohn's disease
9. Expression of gamma-glutamyl-cysteine synthetase in the liver of copper-deficient rats
10. Glutathione in the idiopathic inflammatory bowel diseases: Relationship between colonic glutathione levels and inflammation
11. Chronic glutathione depletion alters expression of enteric inhibitory neurochemicals in the mouse
12. Histochemistry of NADPH-diaphorase, a marker for neuronal nitric oxide synthase, in the peripheral autonomic nervous system of the mouse
13. L-Glutamine supplementation of a high fat diet reduces body weight and attenuates hyperglycemia and hyperinsulinemia in C57BL/6J mice
14. Inhibition of glutathione synthesis in the newborn rat: A model for endogenously produced oxidative stress
15. The preparation and properties of a soluble diphosphopyridine nucleotide cytochrome c reductase
16. Distribution and quantitation of gut neuropeptides in normal intestine and inflammatory bowel diseases
17. Thiobarbituric acid test as a measure of lipid peroxidation in Arab patients with NIDDM
18. Effect of L-glutamine supplementation on impaired glucose regulation during intravenous lipid administration
19. Glutamine preserves liver glutathione after lethal hepatic injury
20. Low blood glutathione levels in healthy aging adults
21. The small intestine
22. Inflammatory bowel disease: Etiology and pathogenesis
23. Adhesion molecules controlling lymphocyte migration
24. Free radical tissue damage: Protective role of antioxidant nutrients
25. Phase II trial of copper/zinc superoxide dismutase (CuZnSOD) in treatment of Crohn's disease
26. Effect of orally administered glutathione on glutathione levels in some organs of rats: Role of specific transporters
27. Glutathione and glutathione ethyl ester supplementation of mice alter glutathione homeostasis during exercise
28. Nitric oxide modulates T-lymphocyte migration in Peyer's patches and villous submucosa of rat small intestine
29. Amelioration of chronic ileitis by nitric oxide synthase inhibition
30. Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase