Ligand-activated progesterone receptor isoform hPR-A is a stronger transactivator than hPR-B for the expression of IGFBP-1 (insulin-like growth factor binding protein-1) in human endometrial stromal cells

Molecular Endocrinology

Volumn 14, Issue 12, 2000, Pages 1954-1961

  Gao, J ^a   Mazella, J ^a   Tang, M ^a   Tseng, L ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA ETHYL 21 HYDROXY 19 NORPREGN 4 ENE 3,20 DIONE; ISOPROTEIN; LIGAND; MEDROXYPROGESTERONE ACETATE; NORETHISTERONE; PROGESTERONE; PROGESTERONE RECEPTOR; PROTEIN HPR A; PROTEIN HPR B; SOMATOMEDIN BINDING PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; DECIDUALIZATION; ENDOMETRIUM; EXPRESSION VECTOR; FEMALE; GENETIC TRANSFECTION; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; STROMA CELL; TRANSACTIVATION;

EID: 0034534160     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.14.12.0564     Document Type: Article

References (32)

1. Regulation of progesterone receptor messenger ribonucleic acid by progestin in human endometrial stromal cells
2. Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle
3. Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors
4. Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function
5. Effect of overexpression of progesterone receptor A on endogenous progestinsensitive endpoints in breast cancer cells
6. Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor
7. An N-terminal inhibitory function, IF, suppresses transcription by the A-isoform but not the B-isoform of human progesterone receptors
8. Definition of a negative modulation domain in the human progesterone receptor
9. Regulation of insulin-like growth factor-binding protein-1 synthesis and secretion by progestin and relaxin in long term cultures of human endometrial stromal cells
10. Effect of progestin, antiprogestin, and relaxin on the accumulation of prolactin and insulin-like growth factor-binding protein-1 messenger ribonucleic acid in human endometrial stromal cells
11. Activation of human insulin-like growth factor binding protein-1 gene promoter by a distal regulatory sequence in a human endometrial adenocarcinoma cell line
12. Human IGF BP-1 gene activation in human endometrium
13. Activation of the insulin-like growth factor binding protein-1 promoter by progesterone receptor in decidualized human endometrial stromal cells
14. Partial characterization of the CCAAT box in the promoter of the hIGFBP-1 gene: Interaction with negatively acting transcription factors in decidualized human endometrial stromal cells
15. Distal Sp3 binding sites in the hIGFBP-1 gene promoter suppress the transcriptional repression in decidualized human endometrial stromal cells: Identification of a novel Sp3 form in decidual cells
16. Identification of a distal regulatory sequence of the human IGFBP-1 gene promoter and regulation by the progesterone receptor in a human endometrial adenocarcinoma cell line
17. Multihormonal regulation of IGFBP-1 promoter activity
18. Glucocorticoids, insulin regulate expression of the human gene for insulin-like growth factor-binding protein- 1 through proximal promoter elements
19. Decidualization of human endometrial stromal cells in vitro: Effects of progestin and relaxin on the ultrastructure and production of decidual secretory proteins
20. Endometrial cells gene activation during implantation, early pregnancy
21. Progestin, estrogen, and IGF-1 stimulate the prolactin receptor mRNA in human endometrial cells
22. Differential effects of progestin and relaxin on the synthesis and secretion of immunoreactive prolactin in long term culture of human endometrial stromal cells
23. High-efficiency transformation of mammalian cells by plasmid DNA
24. Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor
25. Hormone-induced progesterone receptor phosphorylation consists of sequential DNA-independent and DNA-dependent stages: Analysis with zinc finger mutants and the progesterone antagonist ZK98299
26. Firefly luciferase gene: Structure and expression in mammalian cells
27. The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction
28. The 1982 Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection
29. A simple technique for the rescue of early region I mutations into infectious human, adenovirus type 5
30. Helper-free adenovirus type-5 vectors
31. Genomic elements involved in transcriptional regulation of the rabbit surfactant protein-A gene
32. Monoclonal antibodies to human progesterone receptor: Characterization by biochemical and immunohistochemical techniques