In vitro pentamer formation as a biomarker of tacrolimus-related immunosuppressive activity after liver transplantation

Clinical Chemistry and Laboratory Medicine

Volumn 38, Issue 11, 2000, Pages 1209-1211

  Tolou Ghamari, Z ^a   Wendon, J ^a   Tredger, J M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Calcineurin; Liver transplantation; Tacrolimus

Indexed keywords

BIOCHEMICAL MARKER; CALCINEURIN; CALCIUM; FK 506 BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; TACROLIMUS;

ANALYTIC METHOD; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; INTERMETHOD COMPARISON; LIVER TRANSPLANTATION; MICROPARTICLE ENZYME IMMUNOASSAY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECIPIENT;

BIOLOGICAL MARKERS; DRUG MONITORING; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIVER TRANSPLANTATION; TACROLIMUS;

EID: 0034533161     PISSN: 14346621     EISSN: None     Source Type: Journal    
DOI: 10.1515/CCLM.2000.190     Document Type: Article

References (5)

1. Monitoring tacrolimus in liver transplant recipients: A consideration of alternative techniques and the influence of clinical status
2. Detection of the FKBP-calcineurin complex by a simple binding assay
3. Modified pentamer formation assay for measurement of tacrolimus and its active metabolites: Comparison with liquid chromatography-tandem mass spectrometry and microparticle enzyme linked immunoassay
4. Therapeutic drug monitoring of cyclosporine and tacrolimus
5. Calcineurin activity is only partially inhibited in leukocytes of cyclosporine-treated patients