Solvation enthalpies as descriptors of structure - In vitro percutaneous permeation relationship of benzoxazinones regioisomers

Farmaco

Volumn 55, Issue 8, 2000, Pages 563-568

  Minghetti, Paola ^a   Casiraghi, Antonella ^a   Cilurzo, Francesco ^a   Montanari, Luisa ^a   Valmen Monzani, M ^b   Bertolini, Giorgio ^b   Zaliani, Andrea ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b Italfarmaco SpA   (Italy)

Author keywords

Benzoxazinones; In vitro percutaneous absorption; Physicochemical characteristics; Regioisomer; Structure property relationship

Indexed keywords

BENZOXAZINONE DERIVATIVE; HYDROGEN; OCTANOL; WATER;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG SOLUBILITY; ENTHALPY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROGEN BOND; MOLECULAR WEIGHT; SKIN ABSORPTION; SKIN PERMEABILITY; SOLVATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

HUMANS; ISOMERISM; PERMEABILITY; SKIN; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 0034533137     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(00)00048-3     Document Type: Article

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