Effects of endogenous neurotrophins on sympathetic sprouting in the dorsal root ganglia and allodynia following spinal nerve injury

Experimental Neurology

Volumn 164, Issue 2, 2000, Pages 344-350

  Deng, Yan Shen ^a   Zhong, Jin Hua ^a   Zhou, Xin Fu ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

Brain derived neurotrophic factor; Immunohistochemistry; Nerve growth factor; Neurotrophin 3; Pain; Spinal nerve injury

Indexed keywords

ANTISERUM; BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; TYROSINE 3 MONOOXYGENASE;

ADRENERGIC SYSTEM; ADRENERGIC TRANSMISSION; ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NERVE SPROUTING; NONHUMAN; PAIN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SPINAL GANGLION; SPINAL NERVE;

EID: 0034532606     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2000.7432     Document Type: Article

References (51)

1. Intraplantar injection of nerve growth factor into the rat hind paw: Local edema and effects on thermal nociceptive threshold
2. Peripheral administration of nerve growth factor in the adult rat produces a thermal hyperalgesia that requires the presence of sympathetic post-ganglionic neurones
3. NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis
4. Causalgia and other reflex sympathetic dystrophies
5. Sympathetic sprouting in the dorsal root ganglia of the injured peripheral nerve in a rat neuropathic pain model
6. Over-expression of NGF in skin causes formation of novel sympathetic projections to trkA-positive sensory neurons
7. BDNF is involved in sympathetic sprouting in the dorsal root ganglia following peripheral nerve injury in rats
8. Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat
9. Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve
10. NGF involvement in pain induced by chronic constriction injury of the rat sciatic nerve
11. Changes of nerve growth factor synthesis in non-neuronal ceils in response to sciatic nerve transection
12. A role for nerve growth factor in sympathetic sprouting in rat dorsal root ganglia
13. Sympathectomy alleviates mechanical allodynia in an experimental animal model for neuropathy in the rat
14. Effects of sympathectomy on a rat model of peripheral neuropathy
15. Sensory and sympathetic contributions to nerve injury-induced sensory abnormalities in the rat
16. Expression of nerve growth factor in the dorsal root ganglion after peripheral nerve injury
17. Nerve growth factor-induced hyperalgesia in the neonatal and adult rat
18. Upregulation of brain-derived neurotrophic factor and neuropeptide Y in the dorsal ascending sensory pathway following sciatic nerve injury in rat
19. Neurotrophins: Peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity
20. Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia
21. The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule
22. Neurotrophins, nociceptors, and pain
23. Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats
24. The effect of systemically administered recombinant human nerve growth factor in healthy human subjects
25. Expression of dopamine by chick primary sensory neurons and their related targets
26. Reduced sympathetic sprouting occcurs in dorsal root ganglia after axotomy in mice lacking low affinity neurotrophin receptor
27. Adrenergic innervation of rat sensory ganglia following proximal or distal painful sciatic neuropathy: Distinct mechanisms revealed by anti- NGF treatment
28. Wallerian degeneration is required for both neuropathic pain and sympathetic sprouting into the DRG
29. Glial overexpression of NGF enhances neuropathic pain and adrenergic sprouting into DRG following chronic sciatic constriction in mice
30. Nerve growth factor alleviates a painful peripheral neuropathy in rats
31. Endogenous nerve growth factor and neurotrophin 3 act simultanously to ensure the survival of postnatal sympathetic neurons in vivo
32. Peripheral nerve regeneration and neurotrophic factors
33. Hyperalgesia due to nerve damage: Role of nerve growth factor
34. Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord
35. Axotomy upregulates the anterograde transport and expression of brain-derived neurotrophic factor by sensory neurons
36. Sympathetic axons surround nerve growth factor-immunoreactive trigeminal neurons: Observations in mice overexpressing nerve growth factor
37. Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation
38. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity
39. Neuronal-glial differential expression of TGF-alpha and its receptor in the dorsal root ganglia in response to sciatic nerve lesion
40. Contributions of injured and intact afferents to neuropathic pain in an experimental rat model
41. Endogenous neurotrophin-3 is required for the survival of a subpopulation of primary sensory neurons in neonatal rats
42. Injured primary sensory neurons switch phenotype for brain derived neurotrophic factor in the rat
43. Satellite cell-derived neurotrophins induces noradrengic sprouting in the dorsal root ganglia following peripheral nerve injury in the rat
44. Neurotrophins from dorsal root ganglia trigger allodynia after spinal nerve injury in rats
45. Differential expression of the p75 nerve growth factor receptor in glia and neurons of the rat dorsal root ganglia after peripheral nerve transection
46. Mature sympathetic neurons derive neurotrophin-3 from effector tissues in rat
47. Sympathetic neurons in neonatal rats require endogenous neurotrophin-3 for survival
48. An improved procedure for the immunohistochemical localization of nerve growth factor-like immunoreactivity
49. Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons
50. Endogenous nerve growth factor is required for regulation of the low affinity neurotrophin receptor (p75) in sympathetic but not sensory ganglia