A DNase I hypersensitive site near the murine γ1 switch region contributes to insertion site independence of transgenes and modulates the amount of transcripts induced by CD40 ligation

International Immunology

Volumn 12, Issue 12, 2000, Pages 1705-1713

  Adams, K ^a   Ackerly, H ^a   Cunningham, K ^a   Dunnick, W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

CD40 ligand; Gene rearrangement; IL 4; Isotype switching

Indexed keywords

CIS ACTING ELEMENT; DEOXYRIBONUCLEASE I; GLYCOPROTEIN GP 39; IMMUNOGLOBULIN HEAVY CHAIN; INTERLEUKIN 4; RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXON; GENE EXPRESSION; GENE INDUCTION; GENE INSERTION; GENE SWITCHING; GENETIC TRANSCRIPTION; GERM LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; TRANSCRIPTION REGULATION; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD40; DEOXYRIBONUCLEASE I; EXONS; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN GAMMA-CHAINS; IMMUNOGLOBULIN SWITCH REGION; INTERLEUKIN-4; LOCUS CONTROL REGION; MICE; MICE, TRANSGENIC; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC; TRANSGENES;

EID: 0034529998     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/12.12.1705     Document Type: Article

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