Synthesis and evaluation of novel 2-oxo-1,2-dihydro-3-quinolinecarboxamide derivatives as serotonin 5-HT4 receptor agonists

Chemical and Pharmaceutical Bulletin

Volumn 48, Issue 12, 2000, Pages 2003-2008

  Suzuki, M ^a   Ohuchi, Y ^a   Asanuma, H ^a   Kaneko, T ^a   Yokomori, S ^a   Ito, C ^a   Isobe, Y ^a   Muramatsu, M ^a  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Quinolinecarboxamide; Serotonin 5 HT4 receptor stimulating activity; Structure activity relationship

Indexed keywords

2 OXO 1,2 DIHYDRO 3 QUINOLINECARBOXAMIDE DERIVATIVE; 2,3 DIHYDRO 3 ISOPROPYL 2 OXO 1 BENZIMIDAZOLECARBOXYLIC ACID 3ALPHA TROPANYLAMIDE; CISAPRIDE; METOCLOPRAMIDE; MOSAPRIDE CITRATE; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; RENZAPRIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN 4 AGONIST; SEROTONIN 4 RECEPTOR; UNCLASSIFIED DRUG; ZACOPRIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DOG; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; INTESTINE MOTILITY; MUSCLE CONTRACTION; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

EID: 0034529948     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.48.2003     Document Type: Article

References (31)

1. Crystal structure analysis package