Attenuation of luteinizing hormone surges in neuropeptide Y knockout mice

Neuroendocrinology

Volumn 72, Issue 5, 2000, Pages 263-271

  Xu, Ming ^a   Hill, Jennifer W ^a   Levine, Jon E ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Gonadal steroids; Gonadotropin releasing hormone; Gonadotropins; Knock out mice; Neuropeptide Y

Indexed keywords

ESTROGEN; FOLLITROPIN; GONADORELIN; LUTEINIZING HORMONE; NEUROPEPTIDE Y; PROGESTERONE;

ADENOHYPOPHYSIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ESTRUS CYCLE; HORMONAL REGULATION; HORMONE BLOOD LEVEL; KNOCKOUT MOUSE; LUTEINIZING HORMONE RELEASE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ESTRADIOL; FEMALE; GONADOTROPIN-RELEASING HORMONE; LUTEINIZING HORMONE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROPEPTIDE Y; OVARIECTOMY; PHEROMONES; PREGNANCY; PROESTRUS; REPRODUCTION;

EID: 0034528940     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054595     Document Type: Article

References (34)

1. Evidence that neuropeptide Y (NPY) released into the hypophysial-portal circulation participates in priming gonadotropes to the effects of gonadotropin releasing hormone (GnRH)
2. Dynamic changes in neuropeptide Y concentrations in the median eminence in association with preovulatory luteinizing hormone release in the rat
3. Neuropeptide Y potentiates luteinizing hormone (LH)-releasing hormone-stimulated LH surges in pentobarbital-blocked proestrous rats
4. Neuropeptide Y potentiates luteinizing hormone (LH)-releasing hormone-induced LH secretion only under conditions leading to preovulatory LH surges
5. Estrous cycle stage-dependent effects of neuropeptide-Y on luteinizing hormone (LH)-releasing hormone-stimulated LH and follicle-stimulating hormone secretion from anterior pituitary fragments in vitro
6. Neuropeptide Y Y1-receptor stimulation is required for physiological amplification of preovulatory luteinizing hormone surges
7. Role of protein kinase C in facilitation of luteinizing hormone (LH)-releasing hormone-induced LH surges by neuropeptide Y
8. Involvement of the Y-1 receptor subtype in the regulation of luteinizing hormone secretion by neuropeptide Y in rats
9. Role of neuropeptide Y in the regulation of gonadotropin-releasing hormone gene expression in the rat preoptic area
10. Evidence that the inhibition of luteinizing hormone secretion exerted by central administration of neuropeptide Y (NPY) in the rat is predominantly mediated by the NPY-Y5 receptor subtype
11. The role of neuropeptide Y (NPY) in the control of LH secretion in the ewe with respect to season. NPY receptor subtype and the site of action in the hypothalamus
12. Chronic administration of neuropeptide Y into the lateral ventricle starting at 30 days of life delays sexual maturation in the female rat
13. A physiological role for neuropeptide Y in regulating the estrogen/progesterone induced luteinizing hormone surge in ovariectomized rats
14. Neuropeptide Y is a neuromodulator of pulsatile luteinizing hormone-releasing hormone release in the gonadectomized rhesus monkey
15. Stimulation of the gonadotropic axis by the neuropeptide Y receptor Y1 antagonist/Y4 agonist 1229U91 in the male rat
16. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
17. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
18. Endocrine function of neuropeptide Y knockout mice
19. Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice
20. Pituitary LH content and reproductive tract changes during the mouse oestrous cycle
21. Control of the preovulatory release of luteinizing hormone by steroids in the mouse
22. Changes in pulsatile release of neuropeptide-Y and luteinizing hormone (LH)-releasing hormone during the progesterone-induced LH surge in rhesus monkeys
23. Control of luteinizing hormone-releasing hormone pulse generation in nonhuman primates
24. Neuropeptide Y (NPY): A possible role in the initiation of puberty
25. Developmental study of neuropeptide Y-like immunoreactivity in the neurohypophysis and intermediate lobe of the rhesus monkey (Macaca mulatta)
26. Facilitatory role of neuropeptide Y on the onset of puberty: Effect of immunoneutralization of neuropeptide Y on the release of luteinizing hormone and luteinizing-hormone-releasing hormone
27. Estradiol enhances the action of neuropeptide Y on in vivo luteinizing hormone-releasing hormone release in the ovariectomized rhesus monkey
28. Steroid modulation of neuropeptide Y-induced luteinizing hormone releasing hormone release from median eminence fragments from male rats
29. Neuropeptide Y gene expression in the arcuate nucleus is increased during preovulatory luteinizing hormone surges
30. Evidence that neuropeptide Y secretion in the median eminence increases prior to the luteinizing hormone surge in ovariectomized steroid-primed rats: Estimation by push-pull perfusion
31. Immunoneutralization of neuropeptide Y suppresses luteinizing hormone secretion in rabbits
32. Neural correlates of adenohypophyseal LH release in rats
33. Third-ventricular infusion of neuropeptide Y suppresses luteinizing hormone secretion in ovariectomized rhesus macaques
34. Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats