Amyloidogenesis in Familial British dementia is associated with a genetics defect on chromosome 13

Annals of the New York Academy of Sciences

Volumn 920, Issue , 2000, Pages 84-92

  Ghiso, J ^a   Vidal, R ^b   Rostagno, A ^c   Miravalle, L ^a   Holton, J L ^b   Mead, S ^c   Revesz T ^a   Plant, G ^b   Frangione, B ^c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; BRAIN PROTEIN; FURIN; MEMBRANE PROTEIN; PROTEIN PRECURSOR; PROTEIN SUBUNIT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOIDOSIS; BRAIN BLOOD VESSEL; CARBOXY TERMINAL SEQUENCE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 13; CONFERENCE PAPER; FAMILIAL BRITISH DEMENTIA; FAMILIAL DISEASE; GENETIC CODE; GENETIC DISORDER; HUMAN; HUMAN CELL; LIMBIC CORTEX; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; PARENCHYMA; PROTEIN AGGREGATION; PROTEIN DEGRADATION; UNITED KINGDOM;

EID: 0034528382     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06908.x     Document Type: Conference Paper

References (30)

1. Familial cerebral amyloid angiopathy with nonneuritic plaque formation
2. Familial presenile dementia with spastic paralysis
3. Congophilic angiopathy of the brain: A clinical and pathological report on two siblings
4. Familial cerebellar ataxia with cerebrovascular amyloid
5. Cytoskeletal pathology in familial cerebral amyloid angiopathy (British type) with non-neuritic plaque formation
6. A form of familial presenile dementia with spastic paralysis (including the pathological examination of a case)
7. Discussion
8. Discussion
9. Atypical Alzheimer's disease with spastic paresis and ataxia
10. A familial ocurrence of Creutzfeldt-Jacob disease and Alzheimer's disease
11. A typical Gerstmann-Sträussler syndrome of familial spino cerebellar ataxia and Alzheimer's disease?
12. Cerebral amyloid angiopathy: A critical review
13. Familial cerebral amyloid angiopathy (British type) with nonneuritic amyloid plaque formation may be due to a novel amyloid protein
14. C-terminal fragments of α- and β-tubulin form amyloid fibrils in vitro and associate with amyloid deposits of familial CAA, British type
15. Novel gene BRI mutated at its stop codon causs familial British dementia
16. Mass spectrometry of purified amyloid beta protein in Alzheimer's disease
17. Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain
18. N-terminal heterogeneity of parenchymal and cerebrovascular Aβ deposits
19. cDNA sequence analysis, chromosomal assignment and expression pattern of the gene coding for integral membrane protein 2B
20. Unifying features of systemic and cerebral amyloidosis
21. Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
22. Proteolytic processing in the secretory pathway
23. Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia
24. Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing
25. Production of the Alzheimer amyloid beta protein by normal proteolytic processing
26. Alzheimer's soluble amyloid B is a normal component of human urine
27. Amyloid beta-peptide is produced by cultured cells during normal metabolism
28. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
29. Neurodegenerative diseases with cytoskeletal pathology: A biochemical classification