The transmembrane domain of murine α-mannosidase IB is a major determinant of Golgi localization

European Journal of Cell Biology

Volumn 79, Issue 12, 2000, Pages 986-992

  Becker, Burkhard ^a,b   Haggarty, Allison ^a   Romero, Pedro A ^a   Poon, Terry ^a   Herscovics, Annette ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Golgi; Targeting; mannosidase

Indexed keywords

ALPHA MANNOSIDASE; AMINO ACID; CHIMERIC PROTEIN; GLYCAN; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BIOGENESIS; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CHIMERA; CONTROLLED STUDY; CYTOPLASM; DELETION MUTANT; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; FLUORESCENCE MICROSCOPY; GOLGI COMPLEX; HYBRID; KIDNEY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN TARGETING; YEAST;

EID: 0034528352     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00127     Document Type: Article

References (44)

1. Golgi retention of a trans-Golgi membrane protein, galactosyltransferase, requires cysteine and histidine residues within the membrane-anchoring domain
2. A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins
3. Cholesterol and the Golgi apparatus
4. The Saccharomyces cerevisiae processing α1,2-mannosidase is localized in the endoplasmic reticulum, independently of known retrieval motifs
5. The transmembrane and flanking sequences of β1,2-N-Acetylglucosaminyltransferase I specify medial-Golgi localization
6. Golgi localization of glycosyltransferases: More questions than answers
7. The signal anchor and stem regions of the β-galactoside α2,6-sialyltransferase may each act to localize the enzyme to the Golgi apparatus
8. gp25L/emp24/p24 protein family members of the cis-golgi network bind both COPI and II coatomer
9. Bimodal interaction of coatomer with the p24 family of putative cargo receptors
10. Targeting of proteins to the Golgi apparatus
11. Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells
12. Localization of a yeast early Golgi mannosyltransferase, Och1p, involves retrograde transport
13. Glycosidases of the asparagine-linked oligosaccharide processing pathway
14. Importance of glycosidases in mammalian glycoprotein biosynthesis
15. Isolation of a mouse Golgi mannosidase cDNA, a member of a gene family conserved from yeast to mammals
16. Evidence for recycling of the resident medial/trans Golgi enzyme, N-acetylglucosaminyltransferase I, in 1dlD cells
17. α-Mannosidases involved in N-glycan processing show cell specificity and distinct subcompartmentalization within the Golgi apparatus of cells in the testis and epididymis
18. The recycling of ERGIC-53 in the early secretory pathway. ERGIC-53 carries a cytosolic endoplasmic reticulum-exit determinant interacting with COPII
19. Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae
20. ER/Golgi intermediates acquire Golgi enzymes by Brefeldin A-sensitive retrograde transport in vitro
21. Sequence and overexpression of GPP130/ GIMPc: Evidence for saturable pH-sensitive targeting of a type II early Golgi membrane protein
22. Isolation of functional Golgi-derived vesicles with a possible role in retrograde transport
23. Golgi retention signals: Do membranes hold the key?
24. A specific transmembrane domain of a coronavirus E1 glycoprotein is required for its retention in the Golgi region
25. Retention of a cis Golgi protein requires polar residues on one face of a predicted α-helix in the transmembrane domain
26. Sequences within and adjacent to the transmembrane segment of α-2,6-sialyltransferase specify Golgi retention
27. A comparison of the transmembrane domains of Golgi and plasma membrane proteins
28. An investigation of the role of transmembrane domains in Golgi protein retention
29. Localization of proteins to the Golgi apparatus
30. Kin recognition between medial Golgi enzymes in HeLa cells
31. A di-acidic signal required for selective export from the endoplasmic reticulum
32. Association of folding intermediates of glycoproteins with calnexin during protein maturation
33. Glycosyltransferases. Structure, localization, and control of cell type-specific glycosylation
34. Mapping the distribution of Golgi enzymes involved in the construction of complex oligosaccharides
35. Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells
36. Characterization of a novel mouse recombinant processing α-mannosidase
37. Two naturally occurring mouse α-1,2-mannosidase IB cDNA clones differ in three point mutations. Mutation of Phe592 to Ser592 is sufficient to abolish enzyme activity
38. The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in α-COP
39. Efficient export of the vesicular stomatitis virus G protein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifs
40. Isolation of a matrix that binds medial Golgi enzymes
41. Recycling of Golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering
42. The signal for Golgi retention of bovine β1,4-galactosyltransferase is in the transmembrane domain
43. Cell type-dependent variations in the subcellular distribution of α-mannosidase I and II
44. Reversible denaturation of Aequorea green-fluorescent protein: Physical separation and characterization of the renatured protein