Lack of run-down of smooth muscle P2X receptor currents recorded with the amphotericin permeabilized patch technique, physiological and pharmacological characterization of the properties of mesenteric artery P2X receptor ion channels

British Journal of Pharmacology

Volumn 131, Issue 8, 2000, Pages 1659-1666

  Lewis, C J ^a   Evans, R J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Artery; Immunohistochemistry; P2X receptors; Patch clamp; Suramin

Indexed keywords

AMPHOTERICIN; ION CHANNEL; PURINE P2X RECEPTOR; SURAMIN;

ANIMAL TISSUE; ARTERY MUSCLE; ARTICLE; CALCIUM CELL LEVEL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MEMBRANE CURRENT; MESENTERIC ARTERY; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; RAT; REPRODUCIBILITY; SMOOTH MUSCLE CONTRACTILITY; STOICHIOMETRY;

EID: 0034528021     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703744     Document Type: Article

References (43)

1. Channel gating kinetics and synaptic efficacy: A hypothesis for expression of long-term potentiation
2. ATP-activated channels gate calcium entry in single smooth muscle cells from rabbit ear artery
3. A P2X purinoceptor cDNA conferring a novel pharmacological profile
4. New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
5. An antagonist-insensitive P2X receptor expressed in epithelia and brain
6. The past, present and future of purine nucleotides as signalling molecules
7. A P2X purinoceptor expressed by a subset of sensory neurons
8. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels
9. 2+ by speeding recovery of P2X receptors from desensitisation
10. Characterization of P2-purinoceptors in the smooth muscle of the rat tail artery: A comparison between contractile and electrophysiological responses
11. Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2X purinoceptors)
12. Vasoconstriction of guinea-pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP
13. Pharmacological characterization of purinoceptor-mediated constriction of submucosal arterioles in guinea pig ileum
14. Characterization of cultured dorsal root ganglion neuron P2X receptors
15. 5 isoforms
16. The properties of the ATP-induced depolarization and current in single cells isolated from the guinea-pig urinary bladder
17. 1 receptors
18. A study of the desensitization produced by acetylcholine at the motor end-plate
19. 2+-permeable cation channels in mouse, rat and guinea-pig megakaryocytes: A patch clamp study
20. A study on P2X purinoceptors mediating the electrophysiological and contractile effects of purine nucleotides in rat vas deferens
21. 6 subunits in Xenopus oocytes
22. 1 receptors
23. 6 channel subunits co-assemble into a novel heteromeric ATP receptor
24. nGs) on rat mesenteric artery P2X receptor ion channels
25. 3 receptor subunits can account for ATP-gated currents in sensory neurons
26. 2′,3′-O-(2,4,6-Trinitrophenyl) adenosine 5′-triphosphate (TNP-ATP)-a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels
27. 1 receptors: Evidence for separate receptors stimulated by ATP and ADP on human platelets
28. 1 receptors
29. Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: Identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor
30. 3 receptors form stable trimers: A novel structural motif of ligand-gated ion channels
31. 4 receptors in rat vascular smooth muscle: An in situ hybridization and RT-PCR study
32. Neuroreceptor mRNA expression in the rat mesenteric artery develops independently of innervation
33. The properties and distribution of inward rectifier potassium currents in pig coronary arterial smooth muscle
34. Actions mediated by P2-purinoceptor subtypes in the isolated perfused mesenteric bed of the rat
35. Characterization of a P2X-purinoceptor in cultured neurones of the rat dorsal root ganglia
36. 2 receptor: Estimates based on methanethiosulfonate block at T336C
37. Hetero-oligomeric assembly of P2X receptor subunits
38. 5 receptor subunits reveals a novel ATP-gated ion channel
39. The selective P2X purinoceptor agonist, beta,gamma,-methylene-L-adenosine 5′-triphosphate, discriminates between smooth muscle and neuronal P2X purinoceptors
40. A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP
41. 2/3 receptors
42. Differential distribution of two ATP-gated ion channels (P2X receptors) determined by immunohistochemistry
43. Vasoconstrictor and vasodilator responses to various agonists in the rat perfused mesenteric arterial bed: Selective inhibition by PPADS of contractions mediated via P2X-purinoceptors