Deconstructing the interaction of glu-plasminogen with its receptor α-enolase

Fibrinolysis and Proteolysis

Volumn 14, Issue 6, 2000, Pages 327-336

  Andronicos, N M ^a   Baker, M S ^b   Lackmann, M ^c   Ranson, M ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ENOLASE; ENOLASE; GLUCOSE; PLASMINOGEN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONCENTRATION (PARAMETERS); DISSOCIATION; ENZYME BINDING; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME STABILITY; ENZYME STRUCTURE; MOLECULAR INTERACTION; PRIORITY JOURNAL; REACTION ANALYSIS; SPECTROFLUOROMETRY;

EID: 0034527558     PISSN: 13690191     EISSN: None     Source Type: Journal    
DOI: 10.1054/fipr.2000.0090     Document Type: Article

References (39)

1. Directed plasminogen activation at the surface of normal and malignant cells
2. The crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands, ε-aminocaproic acid and 4 trans-4-aminomethylcyclohexane-1-carboxylic acid
3. Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-Å resolution
4. The refined structure of ε-aminocaproic acid complexed human plasminogen kringle 4
5. Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen
6. The structure of plasminogen studied by electron microscopy
7. The compact domain conformation of human glu-plasminogen in solution
8. Characterisation of an extremely large, ligand-induced conformational change in plasminogen
9. 2-terminal lysine forms of plasminogen isolated by affinity chromatography and isoelectric focusing methods
10. Conformational studies of human plasminogen and plasminogen fragments: Evidence for a novel third conformation of plasminogen
11. Interactions of plasminogen with polymerizing fibrin and its derivatives, monitored with a photoaffinity cross-linker and electron microscopy
12. Contributions of the individual kringle domains toward maintenance of the chloride-induced tight conformation of human glutamic acid-1 plasminogen
13. Evidence that the conformation of unliganded human glu-plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 the N-terminal peptide
14. The binding of tranexamic acid to native (Glu) and modified (lys) human plasminogen and its effect on conformation
15. Quantitative determination of the binding of ε-aminocaproic acid to native plasminogen
16. Studies of the conformation changes of plasminogen during activation to plasmin and by 6-aminohexanoic acid
17. Conformation of Lys-plasminogen and the kringle 1-3 fragment of plasminogen analysed by small-angle neutron scattering
18. Stopped-flow kinetic studies of glu-plasminogen. Conformational changes triggered by AH-site ligand binding
19. Stopped-flow kinetic studies of glu-plasminogen. Conformational changes triggered by AH-site ligand binding
20. Kringle 5 of human plasminogen carries a benzamidine-binding site
21. Proximity of the catalytic region and the kringle 2 domain in the closed conformer of plasminogen
22. The effects of fibrinogen and its cleavage products on the kinetics of plasminogen activation by urokinase and subsequent plasmin activity
23. m for (glutamic acid) plasminogen and lysine-plasminogen and effect of certain α,ω-amino acids
24. Studies in the kinetics of plasminogen activation by tissue plasminogen activator
25. The cell biology of the plasminogen system
26. Increased plasminogen binding is associated with metastatic breast cancer cells: Differential expression of plasminogen binding proteins
27. The human ENO1 gene product (recombinant human α-enolase) displays characteristics required for a plasminogen binding protein
28. The role of an enolase-related molecule in plasminogen binding to cells
29. Analysis of the interaction between a synthetic peptide of influenza virus hemagglutinin and monoclonal antibody using an optical biosensor
30. Ligand for EpH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor
31. Conformational changes in plasminogen, their effect on activation and the agents that modulate activation rates-a review
32. The kinetics and affinity of binding of glu-plasminogen specific to the ε-amino group of L-lysine: Its potential application to modified biomaterials
33. Acceleration of plasminogen activation by tissue-plasminogen activator on surface bound histidine-rich glycoprotein
34. Characterisation of cellular binding sites and interactive regions within reactants required for enhancement of plasminogen activation by tPA on the surface of leucocytic cells
35. tPA-dependent activation of C6 glioma-bound plasminogen: A kinetic study
36. Binding of tissue plasminogen activator to cultured human endothelial cells
37. An endothelial cell receptor for plasminogen/tissue plasminogen activator (t-PA). II. Annexin II-mediated enhancement of tPA-dependent plasminogen activation
38. Actin accelerates plasmin generation by tissue plasminogen activator
39. Bound plasminogen is rate-limiting for cell-surface-mediated activation of plasminogen by urokinase