Effect of WEB 2086 on leukocyte adherence in response to hemorrhagic shock in rats

Journal of Trauma - Injury, Infection and Critical Care

Volumn 49, Issue 6, 2000, Pages 1102-1107

  Childs, Ed W ^a   Smalley, David M ^a   Moncure, Michael ^a   Miller, Jerrihlyn L ^a   Cheung, Laurence Y ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Intravital microscopy; Mesenteric venules; Microvascular injury; Platelet activating factor antagonist

Indexed keywords

APAFANT; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL INJURY; BLOOD VESSEL PERMEABILITY; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DRUG EFFICACY; ENDOTHELIUM; HEMORRHAGIC SHOCK; LEUKOCYTE ADHERENCE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL;

EID: 0034526741     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/00005373-200012000-00021     Document Type: Article

References (26)

1. Death in the operating room: An analysis of a multicenter experience
2. The microcirculation and inflammation: Modulation of leukocyte endothelial cell adhesion
3. Platelet-activating factor modulates leukocyte adhesion to endothelium in ischemia-reperfusion
4. Platelet-activating factor stimulates protein tyrosine kinase in hamster cheek pouch microcirculation
5. Detection of platelet-activating factor during traumatic shock
6. Role of platelet-activating factor antagonism in post hemorrhage septic shock in pigs
7. Role of platelet-activating factor in the development of endothelial dysfunction in hemorrhagic hypotension and retransfusion
8. Role of platelet-activating factor antagonism in haemorrhagic shock in pigs
9. Platelet-activating factor: An ether lipid with biological activity
10. Platelet-activating factor increases lung vascular permeability to protein
11. Salutary consequences of blockade of platelet activating factor in hemorrhagic shock
12. Chemistry and biology of acetyl glyceryl ether phosphorylcholine (platelet-activating factor)
13. Leukocyte adherence and sequestration following hemorrhagic shock and total ischemia in rats
14. PAF and CD18 mediate neutrophil infiltration in upper gastrointestinal tract during intra-abdominal sepsis
15. Time course of leukocyte adhesion to endothelium in ischemia-reperfusion
16. Acute microcirculatory effects of platelet-activating factor
17. Platelet activating factor-induced microvascular permeability increases in the cat hindlimb
18. Role of platelet-activating factor in ischemia/reperfusion-induced leukocyte adherence
19. Platelet-activating factor causes venular constriction in the microcirculation
20. Pretreatment with polynittroxl albumin (PNA) inhibits ischemia-reperfusion induced leukocyte-endothelial cell adhesion
21. Platelet activating factor modulates microvascular permeability through nitric oxide synthesis
22. Evidence for a role of platelet activating factor in hypovolemic shock in the rat
23. Platelet-activating factor receptor-antagonist (BN 52021) stabilizes the oxidative-antioxidative balance and attenuates the morphological changes in the gastrointestinal tract in experimental hemorrhagic shock
24. PAF-antagonist administration after hemorrhage-resuscitation prevents splenocyte immunodepression
25. Platelet activating factor (PAF) increases leukocyte adhesion but does not alter vessel diameter in the rat mesenteric microcirculation
26. A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock