FR191512, a novel anti-influenza agent isolated from a fungus strain no. 17415: I Taxonomy, fermentation, isolation, physico-chemical properties and structure elucidation

Journal of Antibiotics

Volumn 53, Issue 12, 2000, Pages 1333-1340

  Nishihara, Y ^a   Tsujii, E ^a   Takase, S ^a   Tsurumi, Y ^a   Kino, T ^a   Hino, M ^a   Yamashita, M ^a   Hashimoto, S ^a  

^a Fermentation Development Lab   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BENZENE DERIVATIVE; BENZOIC ACID DERIVATIVE; BINDING PROTEIN; CARBONYL DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; ENVELOPE PROTEIN; FR 191512; HYDROXYL GROUP; INFLUENZA VIRUS HEMAGGLUTININ; NATURAL PRODUCT; NEW DRUG; POLYKETIDE; POLYPHENOL DERIVATIVE; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS GLYCOPROTEIN; VIRUS SIALIDASE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; FERMENTATION; FUNGUS; FUNGUS CULTURE; INFLUENZA VIRUS A; NONHUMAN; PHYSICAL CHEMISTRY; POWDER; PRIORITY JOURNAL; SPECTROSCOPY; STRAIN DIFFERENCE; STRUCTURE ANALYSIS; TAXONOMY;

EID: 0034526091     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.1333     Document Type: Article

References (13)

1. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase and of growth of a wide range of influenza A and B viruses in vitro
2. NG-011 and NG-012, Novel potentiators of nerve growth factor II. The structure determination of NG-011 and NG-012
3. Inhibition of the infectivity of influenza virus by tea polyphenols
4. Inhibition of influenza virus sialidase and anti-influenza virus activity by plant flavonoids
5. In vivo anti-influenza virus activity of plant flavonoids possessing inhibitory activity for influenza virus sialidase
6. Antifungal macrocyclic polylactones from Penicillium verruculosum
7. FR191512, a novel anti-influenza agent isolated from a fungus strain No.17415. II. Biological properties