Prolidase-activated prodrug for cancer chemotherapy. Cytotoxic activity of proline analogue of chlorambucil in breast cancer MCF-7 cells

Farmaco

Volumn 55, Issue 11-12, 2000, Pages 736-741

  Bielawska, Anna ^a   Bielawski, Krzysztof ^a   Chrzanowski, Krzysztof ^a   Awomir, Woczyski ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Chlorambucil; Prolidase; Proline analogue of chlorambucil

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORAMBUCIL; PRODRUG; PROLINE; PROLINE DIPEPTIDASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CELL VIABILITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS; DRUG SENSITIVITY; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50;

ANTINEOPLASTIC AGENTS, ALKYLATING; BIOTRANSFORMATION; BREAST NEOPLASMS; CELL SURVIVAL; CHLORAMBUCIL; COLLAGEN; DIPEPTIDASES; DNA, NEOPLASM; FEMALE; HUMANS; PRODRUGS; TUMOR CELLS, CULTURED;

EID: 0034525786     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(00)00095-1     Document Type: Article

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