Xeroderma pigmentosum variant heterozygotes show reduced levels of recovery of replicative DNA synthesis in the presence of caffeine after ultraviolet irradiation

Journal of Investigative Dermatology

Volumn 115, Issue 6, 2000, Pages 981-985

  Itoh, Toshiki ^a,b   Linn, Stuart ^a   Kamide, Ryoichi ^c   Tokushige, Hiroyuki ^d   Katori, Nobutada ^d   Hosaka, Yoshiaki ^d   Yamaizumi, Masaru ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KUMAMOTO UNIVERSITY   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d SHOWA UNIVERSITY   (Japan)

Author keywords

DNA polymerase eta; DNA replication; Mutations

Indexed keywords

ARTICLE; CELL SURVIVAL; CLINICAL ARTICLE; CLINICAL FEATURE; DNA POLYMORPHISM; DNA REPAIR; DNA SYNTHESIS; EXON; FRAMESHIFT MUTATION; GENE DELETION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; ISRAEL; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTECTION; SEQUENCE ANALYSIS; SKIN CANCER; SKIN FIBROBLAST; SUN; ULTRAVIOLET RADIATION; XERODERMA PIGMENTOSUM;

EID: 0034521292     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00154.x     Document Type: Article

References (19)

1. The influence of caffeine on cell survival in excision-proficient and excision-deficient xeroderma pigmentosum and normal human cell strains following ultraviolet-light irradiation
2. Xeroderma pigmentosum and Cockayne syndrome
3. A new UV-sensitive syndrome not belonging to any complementation groups of xeroderma pigmentosum or Cockayne syndrome: Siblings showing biochemical characteristics of Cockayne syndrome without typical manifestations
4. ζ syndrome, a new general category of photosensitive disorder with defective DNA repair, is distinct from xeroderma pigmentosum variant and rodent complementation group
5. A simple method for diagnosing xeroderma pigmentosum variant
6. ζ syndrome, a photosensitive disorder with defective DNA repair
7. A newly identified patient with clinical xeroderma pigmentosum phenotype has a nonsense mutation in the DDB2 gene and incomplete repair in (6-4) photoproducts
8. Reinvestigation of the classification of five cell strains of xeroderma pigmentosum group E with reclassification of three of them
9. hRAD30 mutations in the variant form of xeroderma pigmentosum
10. Xeroderma pigmentosum
11. Cockayne's syndrome and tricho-thiodystrophy: Defective repair without cancer
12. Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation
13. Repair of ultraviolet light damage in a variety of human fibroblast cell strains
14. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta
15. Human damage-specific DNA binding protein p48: Characterization of XPE mutations and regulation following UV-irradiation
16. Relationship of xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A
17. Semiconservative deoxyribonucleic acid synthesis in unirradiated and ultraviolet-irradiated xeroderma pigmentosum and normal human skin fibroblasts
18. Molecular mechanisms of DNA repair inhibition by caffeine
19. Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta