Neonatal inoculation with the protein-bound polysaccharide PSK increases resistance of adult animals to challenge with syngeneic tumor cells and reduces azoxymethane-induced precancerous lesions in the colon

Cancer Epidemiology Biomarkers and Prevention

Volumn 9, Issue 12, 2000, Pages 1313-1322

  Matsunaga, Kenichi ^a   Iijima, Hiroko ^a   Kobayashi, Hiroshi ^b  

^a KUREHA CORPORATION   (Japan)

^b Sapporo Cancer Seminar Foundation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; CD4 ANTIGEN; CD8 ANTIGEN; KRESTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CELL SURVIVAL; COLON ADENOCARCINOMA; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; LUNG TRANSPLANTATION; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SURVIVAL TIME; THYMECTOMY;

ADENOCARCINOMA; ADJUVANTS, IMMUNOLOGIC; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; AZOXYMETHANE; CARCINOGENS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; COLON; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, NUDE; NEOPLASM TRANSPLANTATION; PRECANCEROUS CONDITIONS; PROTEOGLYCANS; RATS; RATS, INBRED F344; SURVIVAL ANALYSIS;

EID: 0034521224     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Immunological status of the host injected with MuLV at birth
2. Suppression of specific and nonspecific immune responses in rats injected with Friend or Gross virus
3. Protection of adult BALB/c mice against MOPC315 myeloma by neonatal administration of monoclonal anti-idiotypic antibody to MOPC 315 IgA
4. Chemically defined immunomodulators and interferon inducers
5. PSK as a chemopreventive agent
6. Anti-metastatic effect of PSK, a protein-bound polysaccharide, an overview
7. Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer
8. Randomized controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer
9. Krestin (PSK)
10. Suppression of azoxymethane-induced rat colon aberrant crypt foci by dietary protocatechuic acid
11. Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings
12. Survival surgery: Removal of the spleen or thymus
13. Kinetics of mature T-cell development in the thymus
14. Detection of DNA strands in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
15. Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin)
16. Protein measurement with Folin phenol reagent
17. In vitro demonstration of thymic hormone in the mouse by conversion of precursor cells into lymphocytes
18. Chemical synthesis of a peptide fragment of thymopoietin II that induces selective T cell differentiation
19. Immune mechanisms in homotransplantation. II. Quantitative assay of the immunologic activity of lymphoid cells stimulated by tumor homograft
20. Reduced natural killer activity in female mice after neonatal exposure to diethylstilbestrol
21. Long-term effects of neonatal steroid exposure of mammary gland development and tumorigenesis in mice
22. Seven-day administration of recombinant human granulocyte colony-stimulating factor to newborn rats modulation of neonatal neutrophilia myelopoiesis and Group B Streptococcus sepsis
23. Fate and distribution of antitumor protein-bound polysaccharide PSK (Krestin)
24. Mechanistic consideration in chemopreventive drug development
25. Aberrant crypts as a biomarker for colon cancer; evaluation of potential chemopreventive agents in the rats
26. Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents
27. Inhibition of chemical carcinogenesis