A synthetic nonapeptide derived from the sequence of a platelet type I collagen receptor inhibits type I collagen-mediated platelet aggregation

American Journal of the Medical Sciences

Volumn 320, Issue 6, 2000, Pages 362-367

  Chiang, T M ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Collagen; Platelet; Platelet aggregation; Platelet aggregation inhibitor; Receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; COLLAGEN TYPE 1; COLLAGEN TYPE 1 RECEPTOR; COMPLEMENTARY DNA; GLYCYLGLUTAMYLLEUCYLTYROSYLLYSYLCYSTEINYLISOLEUCYLLEUCYLTYROSINE; NONAPEPTIDE; THROMBOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA; ARTICLE; BINDING SITE; DOSE RESPONSE; NONHUMAN; PROTEIN PHOSPHORYLATION; RABBIT; THROMBOCYTE AGGREGATION INHIBITION;

EID: 0034518415     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000441-200012000-00002     Document Type: Article

References (17)

1. Isolation and purification of collagen α1(I) receptor from human platelet membranes
2. Disturbed platelet aggregation to collagen associated with an antibody against an 85/90 kDa platelet glycoprotein in a patient with prolonged bleeding time
3. Identification of glycoprotein IV (CD 36) as a primary receptor for platelet-collagen adhesion
4. A patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesion
5. Cloning, characterization, and functional studies of a nonintegrin platelet receptor for type I collagen
6. A synthetic peptide derived from the sequence of a type I collagen receptor inhibits type I collagen-mediated platelet aggregation
7. Interaction of a chick skin collagen fragment (α1-CB5) with human platelets. Biochemical studies during the aggregation and release reaction
8. Aggregation of platelets by adenosine diphosphate and its reversal
9. Covalent structure of collagen: Amino acid sequence of α1(III)-CB5 from type III collagen of human liver
10. Covalent structure of collagen: Amino acid sequence of α1(III)-CB9 from type III collagen of human liver
11. Two improved and simplified methods for the spectrophotometric determination of hydroxyproline
12. Collagen-platelet interaction: Separate receptor sites for types I and III collagen
13. Binding of collagen α1 chain to human platelets
14. Effects of the recombinant non-integrin platelet collagen receptor, P65 on platelet activation induced by convulxin
15. Thrombin-induced protein phosphorylation in human platelets
16. Relationship between phosphorylation of blood platelet proteins and secretion of platelet granule constituents. I. Effect of different aggregation agents
17. Collagen-platelet interaction