Heterogeneity in the CagA gene of Helicobacter pylori and its clinical role

Journal of Gastroenterology

Volumn 35, Issue 12, 2000, Pages 945-946

  Mine, T ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL DNA; BACTERIAL PROTEIN; CYTOKINE; CYTOTOXIN; MEMBRANE PROTEIN; VIRULENCE FACTOR;

BACTERIAL GENE; BACTERIAL VIRULENCE; CONTROLLED STUDY; EDITORIAL; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC HETEROGENEITY; HELICOBACTER PYLORI; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; JAPAN; MARKER GENE; MOLECULAR GENETICS; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; RISK ASSESSMENT; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA; STOMACH DISEASE;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; GENES, BACTERIAL; HELICOBACTER PYLORI; HUMANS;

EID: 0034518027     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350070011     Document Type: Editorial

References (17)

1. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
2. Helicobacter pylori infection and the risk of gastric carcinoma
3. Helicobacter pylori infection and gastric lymphoma
4. The complete genome sequence of the gastric pathogen Helicobacter pylori
5. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the cytotoxin
6. Ordered cosmid library and high-resolution physical-genetic map of Helicobacter pylori strain NCTC11638
7. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: Evidence of linkage to cytotoxin production
8. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer
9. Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan
10. Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity
11. Expression of 120 kilodalton protein and cytotoxicity in Helicobacter pylori
12. Rapid fingerprinting of Helicobacter pylori by polymerase chain reaction and restriction fragment length polymorphism analysis
13. Restriction fragment length polymorphism in the adhesin gene hpaA of Helicobacter pylori
14. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: Association of specific vacA types with cytotoxin production and peptic ulceration
15. Analyses of the cag pathogenicity island of Helicobacter pylori
16. Heterogeneity found in the cagA gene of Helicobacter pylori from Japanese and non-Japanese isolates
17. Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori