Fixation of new alleles and the extinction of small populations: Drift load, beneficial alleles, and sexual selection

Evolution

Volumn 54, Issue 6, 2000, Pages 1855-1861

  Whitlock, M C ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Beneficial mutations; Compensatory mutations; Conservation genetics; Drift load; Genetic drift; Mutation meltdown; Sexual selection

Indexed keywords

ALLELE; EFFECTIVE POPULATION SIZE; EXTINCTION; GENETIC DRIFT; MUTATION; POPULATION GENETICS;

ANIMALIA;

EID: 0034515647     PISSN: 00143820     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0014-3820.2000.tb01232.x     Document Type: Article

References (31)

1. Evolution by small steps and rugged landscapes in the RNA virus φ6
2. Mutation accumulation in finite outbreeding and inbreeding populations
3. The mutation load in Drosophila
4. Evolutionary dynamics of fitness recovery from the debilitating effects of Muller's ratchet
5. Effective population size/adult population size ratios in wildlife: A review
6. The rate and effects distribution of viability mutations in Drosophila: Minimum distance estimation
7. The effect of linkage on limits to artificial selection
8. The evolutionary genetics of male life-history characters in Drosophila melanogaster
9. The distribution of mutation effects on viability in Drosophila melanogaster
10. Nature of deleterious mutation load in Drosophila
11. Risk of population extinction from fixation of new deleterious mutations
12. Mutation and conservation
13. Risk of population extinction from fixation of deleterious and reverse mutations
14. Dynamics of adaptation and diversification: A 10,000-generation experiment with bacterial populations
15. Mutational meltdown in sexual populations
16. Mutation accumulation and the extinction of small populations
17. Perspective: Spontaneous deleterious mutation
18. Fixation of beneficial mutations in a population of changing size
19. Mate choice increases a component of offspring fitness in fruit flies
20. Compensating for our load of mutations: Freezing the meltdown of small mutations
21. Inbreeding in artificial selection programs
22. Effective size of populations under selection
23. Mutation and extinction: The role of variable mutational effects, synergistic epistasis, beneficial mutations, and degree of outcrossing
24. Call duration as an indicator of genetic quality in male gray tree frogs
25. Dispersal and the genetic properties of metapopulations
26. Factors affecting the genetic load in Drosophila: Synergistic epistasis and correlations among fitness components
27. The panda and the phage: Compensatory mutations and the persistence of small populations