Cytosolic calcium handling in islets of normal Wistar and diabetic Goto Kakizaki rats in the presence of glucose and truncated glucagon-like peptide 1 (7-36) amide

Annals of the New York Academy of Sciences

Volumn 921, Issue , 2000, Pages 464-468

  Marie, Jean Claude ^a   Bailbe, Danielle ^b  

^a INSERM   (France)

^b EUROPEAN SPACE AGENCY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCIUM ION; GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE; GLUCOSE; INSULIN;

ANIMAL MODEL; ANIMAL TISSUE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; EXOCYTOSIS; INSULIN LIKE ACTIVITY; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET CELL; RAT;

ANIMALIA;

EID: 0034513756     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb07016.x     Document Type: Conference Paper

References (18)

1. Pancreatic β-cell receptors and G proteins coupled to adenylyl cyclase
2. Cell-specific localization of G protein α-subunits in the islets of Langerhans
3. 2+ channel of rat pancreatic β-cell in a cAMP-dependent manner
4. Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting βTC3-cells by enhancement of intracellular calcium mobilization
5. Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1 (7-36)
6. Glucagon-like peptidel elevates cytosolic calcium in pancreatic β-cells independently of protein kinase A
7. 2+ sequestration in diabetic mouse islets of Langerhans
8. 2+ response to glucose as an indicator of impairment of pancreatic β-cell function
9. Metabolic, ionic and secretory response to D-glucose in islets from rats with acquired or inherited non-insulin-dependent diabetes
10. Cross-talk between the cAMP and inositol triphosphate-signalling pathways in pancreatic b-cells
11. 2+
12. i-reducing action of cAMP in rat pancreatic β-cells: Involvement of thapsigargin-sensitive stores
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14. Protein kinase A-dependent and independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells
15. + channel-independent pathway of glucose signaling in rat pancreatic islets
16. 2+-ATPase are differentially expressed in normal and diabetic islets of Langerhans
17. 2+ response to glucose in diabetic GK rat
18. Abnormal cAMP content and insulin release in islets of spontaneously diabetic GK rats