Oncogene activation and tumor suppressor gene inactivation find their sites of expression in the changes in time and space of the age-adjusted cancer incidence rate

In Vivo

Volumn 14, Issue 6, 2000, Pages 725-734

  Kodama, M ^a   Kodama, T ^a   Murakami, M ^a  

^a Kodama Res Inst of Prev Medicine   (Japan)

Author keywords

Environmental hormone; Equilibrium model; Inter tumor linkage; Oncogene tumor suppressor gene complex; Skin cancer; The law of mass action; The least square method of Gauss; The Network theory of cancer risk

Indexed keywords

AGE; ARTICLE; CANCER; CANCER INCIDENCE; CANCER RISK; CARCINOGENESIS; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GENE INACTIVATION; GENE LINKAGE GROUP; HORMONE DEPENDENCE; HUMAN; HUMAN TISSUE; MALE; ONCOGENE; SEX LINKAGE; SKIN CANCER; SPACE; TIME; TUMOR SUPPRESSOR GENE;

EID: 0034511767     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Intertumor linkage linkage of age-adjusted incidence rate in 15 human neoplasias of both sexes
2. Markers of mathematics
3. The regularity of intersteroidal relations in urine as related to the law of mass action
4. Interrelation between Western type cancers and Non-Western type cancers as regards their risk variations in time and space. V. Mathematical analysis of the environment-sensing signal transmission system in carcinogenesis
5. Chronological transition of the Age-Adjusted Incidence Rates (AAIRs) of 20 major neoplasias from early 1960s to mid 1980s
6. Possible implication of environmental hormones in the recent risk increase of cancers of the skin, and the liver, but not of the female breast worldwide
7. Topological transition of the parametric expression site of tumor suppressor inactivation as a marker evidence of environmental hormone-oriented cancer risk increase