Amino acid residues in α-helix-3 of human uteroglobin are critical for its phospholipase A2 inhibitory activity

Annals of the New York Academy of Sciences

Volumn 923, Issue , 2000, Pages 307-311

  Chowdhury, Bhabadeb ^a   Mantile Selvaggi, Giuditta ^a,b   Kundu, Gopal C ^a,c   Miele, Lucio ^a,d   Cordella Miele, Eleonora ^a,e   Zhang, Zhongjian ^a   Mukherjee, Anil B ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

^c NATIONAL CENTRE FOR CELL SCIENCE   (India)

^d LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^e Department of Anesthesiology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PHOSPHOLIPASE A2; UTEROGLOBIN;

ALPHA HELIX; CHROMOSOME 11Q; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ASSAY; ENZYME INHIBITION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0034509632     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb05539.x     Document Type: Conference Paper

References (37)

1. Blastokinin: Inducer and regulator of blastocyst development in the rabbit uterus
2. Uteroglobin: A hormone sensitive endometrial protein involved in blastocyst development
3. Uteroglobin: A novel cytokine?
4. Uteroglobin and uteroglobin-like proteins: The uteroglobin family of proteins
5. Expression of Clara cell 10-kDa gene in the human endometrium and its relationship to ovarian menstrual cycle
6. Tissue-specific expression of the gene coding for human Clara cell 10-kD protein, a phospholipase A2-inhibitory protein
7. Detection of a uteroglobin-like phospholipase A2 inhibitory protein in the circulation of rabbits
8. Isolation of human uteroglobin from blood filtrate
9. Purification and partial amino acid sequence of human urine protein 1: Evidence for homology with rabbit uteroglobin
10. Binding of steroids to uteroglobin
11. Identification, cellular localization, isolation, and characterization of human Clara cell-specific 10 kd protein
12. The binding of methylsulfonylpolychloro-biphenyls to uteroglobin
13. Binding of retinoids to uteroglobin
14. Characterization of two new crystal forms of uteroglobin
15. Crystallization and preliminary crystallographic data of rabbit uteroglobin
16. Purification and quaternary structure of the hormonally induced protein uteroglobin
17. N-terminal sequences of uteroglobin and its precursor
18. Use of molecular replacement in the structure determination of the P21212 and the P21 (pseudo P21212) crystal forms of oxidized uteroglobin
19. Refinement of the C222 (1) crystal form of oxidized uteroglobin at 1.34 Å resolution
20. Crystallization and characterization of the recombinant human Clara cell 10-kDa protein
21. Recombinant human uteroglobin suppresses cellular invasiveness via a novel class of high-affinity cell surface binding site
22. Uteroglobin (UG) suppresses extracellular matrix invasion by normal and cancer cells that express the high-affinity cell UG-binding proteins
23. Binding of uteroglobin to microsomes and plasmatic membranes
24. Human uteroglobin gene: Structure, subchromosomal localization, and polymorphism
25. Amino-acid and cDNA nucleotide sequences of human Clara cell 10-kDa protein
26. Human CC10 gene expression in airway epithelium and subchromosomal locus suggest linkage to airway disease
27. Cloning and characterization of the mouse Clara cell specific 10-kDa protein gene: Comparison of the 5′-flanking region with the human, rat, and rabbit gene
28. Mouse Clara cell 10-kDa (CC10) protein: cDNA nucleotide sequence and molecular basis for the variation in proges: Terone binding of CC10 from different species
29. Tissue-specific expression, hormonal regulation, and 5′-flanking gene region of the rat Clara cell 10-kDa protein: Comparison to rabbit uteroglobin
30. Cloning of a Syrian hamster cDNA related to sexual dimorphism: Establishment of a new family of proteins
31. High level bacterial expression of uteroglobin, a dimeric eukaryotic protein with two interchain disulfide bridges, in its natural quaternary structure
32. Human Clara cell 10-kDa protein is the Counterpart of rabbit uteroglobin
33. Human CC10, the homologue of rabbit uteroglobin: Genomic cloning, chromosomal localization, and expression in endometrial cell lines
34. Uteroglobin inhibits phospholipase A2 activity
35. Novel anti-inflammatory peptides from the region of highest similarity between uteroglobin and lipocortin I
36. Anti-inflammatory peptides (antiflammins) inhibit synthesis of platelet-activating factor, neutrophil aggregation and chemotaxis, and an intradermal inflammatory reaction
37. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding