The difference in the carboxy-terminal sequence is responsible for the difference in the activity of chicken and rat liver fructose-2,6-bisphosphatase

Biological Chemistry

Volumn 381, Issue 12, 2000, Pages 1195-1202

  Zhu, Z ^a   Ling, S ^a   Yang, Q H ^a   Li, L ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

6 Phosphofructo 2 kinase; Fructose 2,6 bisphosphatase; Kinetic property; Mutagenesis; Separate domain

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; ALANINE; AMINO ACID; FRUCTOSE 2,6 BISPHOSPHATASE; GLUTAMIC ACID; LIVER ENZYME; PROLINE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHICKEN; CHIMERA; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; KINETICS; LIVER; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; RESIDUE ANALYSIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CHICKENS; GENE DELETION; KINETICS; LIVER; MUTAGENESIS, SITE-DIRECTED; PHOSPHOFRUCTOKINASE-2; PHOSPHORIC MONOESTER HYDROLASES; RATS; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; GALLUS GALLUS;

EID: 0034507717     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2000.147     Document Type: Article

References (28)

1. Expression of bovine heart fructose 6-phosphate,2-kinase:fructose 2,6-bisphosphatase and determination of the role of the carboxyl terminus by mutagenesis
2. Molecular cloning, sequence analysis, and expression of a human liver cDNA coding for fructose-6-P,2-kinase:fructose-2,6-bisphosphatase
3. Evolution of a bifunctional enzyme: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
4. Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase on adenylate kinase
5. 5′ flanking sequence and structure of a gene encoding rat 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
6. Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades
7. Tissue distribution, immunoreactivity, and physical properties of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
8. The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies
9. Covalent control of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: Insights into autoregulation of a bifunctional enzyme
10. N- and C-termini modulate the effects of pH and phosphorylation on hepatic 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase
11. Preliminary X-ray analysis of a truncated form of recombinant fructose-2,6-bisphosphatase
12. Crystal structure of the rat liver fructose-2,6-bisphosphatase based on selenomethionine multiwavelength anomalous dispersion phases
13. Isolation of a cDNA for chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
14. Expression of chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in Escherichia coli
15. Separate bisphosphatase domain of chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: The role of the COOH-terminal tail in modulating enzyme activity
16. Evidence for NH2- and COOH-terminal interactions in rat 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
17. Complete amino acid sequence of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
18. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: A metabolic signaling enzyme
19. Assays of protein science
20. Mammalian 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: A bifunctional enzyme that controls glycolysis
21. Bovine heart fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase: Complete amino acid sequence and localization of phosphorylation sites
22. Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase
23. Evidence for a phosphoenzyme intermediate in the reaction pathway of rat hepatic fructose-2,6-bisphosphatase
24. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
25. Effect of replacement of the amino and the carboxyl termini of rat testis fructose 6-phosphate, 2-kinase:fructose 2,6-biphosphatase with those of the liver and heart isozymes
26. Bovine brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Evidence for a neural-specific isozyme
27. Mutations in the charged residues of the amino terminus of rat liver fructose 6-phosphate,2-kinase:fructose 2,6-bisphosphatase: Effects on regulation
28. Low concentration of inducer favors production of active form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in Escherichia coli