Platelet-leukocyte interactions in coronary heart disease: Pathophysiology, clinical relevance, pharmacological modulation;Interactions leucoplaquettaires au cours de l'insuffisance coronarienne: Physiopathologie, pertinence clinique, modulation pharmacologique

Journal des Maladies Vasculaires

Volumn 25, Issue 5, 2000, Pages 343-348

  Hezard N ^a   Metz, D ^a   Garnotel, R ^a   Droulle C ^a   Potron, G ^a   Nguyen, P ^a  

^a SERVICE DE DERMATOLOGIE   (France)

Author keywords

2 integrins; GPIIb IIIa antagonist; Inflammation; Leukocyte; P selectin; Platelet

Indexed keywords

BETA2 INTEGRIN; FIBRINOGEN; FIBRINOGEN RECEPTOR; INTEGRIN; LIGAND; PADGEM PROTEIN; UNCLASSIFIED DRUG;

ANGINA PECTORIS; ARTICLE; ATHEROGENESIS; BLOOD CLOTTING; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DILATATION; CORONARY ARTERY DISEASE; ENDOTHELIUM CELL; HUMAN; INFLAMMATION; ISCHEMIC HEART DISEASE; LEUKOCYTE; NEUTROPHIL; PATHOPHYSIOLOGY; REPERFUSION; THROMBOCYTE; THROMBOCYTE FUNCTION; UNSTABLE ANGINA PECTORIS;

ANGINA PECTORIS; ANGINA, UNSTABLE; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANTIBODIES, MONOCLONAL; ANTICOAGULANTS; ANTIGENS, CD18; ASPIRIN; BLOOD PLATELETS; CHEMOTAXIS, LEUKOCYTE; CORONARY ARTERY BYPASS; CORONARY DISEASE; CYTOKINES; FIBRINOGEN; HEPARIN; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; LEUKOCYTES; LIGANDS; MACROPHAGE-1 ANTIGEN; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; NEUTROPHILS; P-SELECTIN; PLATELET ADHESIVENESS; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; THROMBOSPONDINS; TYROSINE;

EID: 0034507609     PISSN: 03980499     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen
2. Structure and function of the leukocyte adhesion molecules CD11/CD18
3. P-selectin-β2-integrin cross-talk : A molecular mechanism for polymorphonuclear leukocyte recruitment at the site of vascular damage
4. Neutropil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the β2-integrin CD11b/CD 18
5. The biological properties of interleukin-1
6. Association of neutrophils with platelet aggregates in unstable angina. Should we alter therapy ?
7. Platelet/polymorphonuclear leucocyte interaction in dynamic conditions : Evidence of adhesion cascade and croos talk between P-selectin and the β2-integrin CD11b/CD18
8. Independent prognostic value of elevated C-reactive protein in unstable angina
9. Effect of SR121566A, a potent GPIIb/IIIa antagonist on platelet-mediated thrombin generation in vitro and in vivo
10. Increased proinflammatory cytokines in patients with chronic stable angina and their reduction by aspirin
11. Potential mechanisms for a proinflammatory vascular cytokine response to coagulation activation
12. Treatment with a GPIIb/IIIa antagonist inhibits thrombin generation in platelet rich plasma from patients
13. Specific accumulation of circulating monocytes and polymorphonuclear leukocytes on platelet thrombi in a vascular injury model
14. Increased platelet responsiveness following coronary stenting. Heparin as a possible aetiological factor in stent thrombosis
15. The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia
16. Evidence for prothrombotic effects of exercise and limited protection by aspirin
17. Novel inflammatory markers of coronary risk. Theory versus practice
18. Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces
19. Leucocyte activation with platelet adhesion after coronary angioplasty : A mechanism for recurrent disease ?
20. Effect of glycoprotein IIb/IIIa receptor blockade on recovery of coronary flow and left ventricular function after the placement of coronary-artery stents in acute myocardial infarction
21. Induction of cytokine expression in leukocytes by binding of thrombin-stimulated platelets
22. Effect of glycoprotein IIb/IIIa receptor blockade on platelet-leukocyte interaction and surface expression of the leukocyte integrin Mac-1 in acute myocardial infarction
23. Increased neutrophil-platelet adhesion in patients in unstable angina
24. Leucocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets
25. Circulating platelet-neutrophil complexes represent a subpopulation of activated neutrophils primed for adhesion, phagocytosis and intracellular killing
26. Tissue thromboplastin activity of isolated human monocytes
27. Glycoprotein IIb/IIIa receptor antagonist Tirofiban inhibits thrombin generation during cardiopulmonary bypass in baboons
28. Neutrophil but not monocyte activation inhibits P-selectin-mediated platelet adhesion
29. Infections, inflammation, and the risk of coronary heart disease
30. Expression cloning of a functional glycoprotein ligand for P-selectin
31. Differential effects of anticoagulants on the activation of platelets ex vivo
32. Glycoprotein IV (GPIV), a non-integrin thrombospondin receptor mediates platelet-monocyte adhesion
33. Rapid secretion of intracellularly pre-stored interleukin-8 from rabbit platelets upon activation
34. Human prothrombinase complex assembly and function on isolated peripheral blood cell populations
35. Functional prothrombinase complex assembly on isolated monocytes and lymphocytes
36. CR3 (CD11b/CD18) espresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopoly-saccharide
37. Platelet activation with unfractionated heparin at therapeutic concentrations and comparison with a low-molecular-weight heparin and with a direct thrombin inhibitor
38. Modulation of platelet-neutrophil interaction with pharmacological inhibition of fibrinogen binding to platelet GPIIb/IIIa receptor
39. Membrane asymetry and blood coagulation