Relationship between plasma ammonia concentration and β-N- acetylhexosaminidase isoenzyme activities in liver cirrhosis

Clinical Chemistry and Laboratory Medicine

Volumn 38, Issue 12, 2000, Pages 1237-1241

  Perez L F ^a   Casal, A ^a   Rojas, P ^a   Tutor, J C ^a  

^a University Hospital of Santiago de Compostela   (Spain)

Author keywords

Enzyme inactivation; Liver disease; Plasma ammonia; N Acetylhexosaminidase isoenzymes

Indexed keywords

AMMONIA; BETA N ACETYLHEXOSAMINIDASE; BETA N ACETYLHEXOSAMINIDASE A; BETA N ACETYLHEXOSAMINIDASE B; BIOCHEMICAL MARKER; ISOENZYME;

ADULT; AGED; AMMONIA BLOOD LEVEL; ARTICLE; CELL CULTURE; CELL STRAIN HEPG2; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; CULTURE MEDIUM; DISEASE MARKER; ENZYME ACTIVITY; ENZYME RELEASE; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; LIVER CIRRHOSIS; LIVER INJURY; MALE; PLASMA; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 0034500408     PISSN: 14346621     EISSN: None     Source Type: Journal    
DOI: 10.1515/cclm.2000.195     Document Type: Article

References (29)

1. Natural history and inherited disorders of a lysosomal enzyme, β-hexosaminidase
2. Intermediate forms of human β-N-acetylhexosaminidase lack activity towards 4-methylumbelliferyl-β-N-acetylglucosaminidase-6-sulphate
3. Immunoassay of β-hexosaminidase isoenzymes in serum in patients with raised total activities
4. Lysosomes and human liver disease: A biochemical and immunohistochemical study of β-hexosaminidase
5. β-Hexosaminidase in serum from patients with cirrhosis and cholestasis
6. β-Hexosaminidase in bile and plasma from patients with cholestasis
7. Isoenzyme pattern of serum β-hexosaminidase in liver disease, alcohol intoxication and pregnancy
8. Immunohistochemical demonstration of β-hexosaminidase in cirrhotic and cholestatic human livers with a monoclonal antibody
9. Serum β-N-actylhexosaminidase as a discriminant between malignant and benign extrahepatic biliary obstruction: Comparison with carcinoembryonic antigen
10. Clinical evaluation of serum N-acetyl-β-D-glucosaminidase as a liver function test
11. Release of β-hexosaminidase isoenzymes in cultured human fibroblasts
12. Liver disease and serum hexosaminidase levels. Studies in a human hepatoma cell-line (Hep G2 cells)
13. The effect of porta-caval shunt, ammonia infusion and alcohol administration on rat plasma β-hexosaminidase
14. Assay of β-N-acetylhexosaminidase isoenzymes in different biological specimens by means of determination of their activation energies
15. Thermodynamic characterization of the mutated isoenzyme A of β-N-acetylhexosaminidase in GM2-gangliosidosis B1 variant
16. Enzymatic measurement of total bile acids adapted to the Cobas Fara centrifugal analyzer
17. Enzymes
18. Assay of serum/plasma β-N-acetylhexosaminidase isoenzymes by heat inactivation using a spectrophotometric method adapted to a centrifugal analyzer
19. Serum β-hexosaminidase isoenzymes are precursor forms
20. Serum β-hexosaminidase isoenzyme: A sensitive marker for alcohol abuse
21. Increases and time-course variations in β-hexosaminidase isoenzyme B and carbohydrate-deficient transferrin in serum from alcoholics are similar
22. Isoenzymes of N-acetyl-β-glucosaminidase from human liver and serum: Separation by electrophocusing in thin layers of polyacrylamide gel
23. 4 poisoning in the rat
24. Principles of diagnostic enzymology
25. Kinetic methods for determination of isoenzyme activities
26. Rat plasma clearance rate and organ distribution of β-hexosaminidase isoenzymes from human serum
27. Can a simple fasting arterial ammonia predict the presence of cirrhosis?
28. Activity of isoenzyme A of N-acetyl-β-glucosaminidase in fibrotic liver tissue