β-adrenergic blockade augments glucose utilization in horses during graded exercise

Journal of Applied Physiology

Volumn 89, Issue 3, 2000, Pages 1086-1098

  Geor, Raymond J ^a,b   Hinchcliff, Kenneth W ^a   Sams, Richard A ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b Kentucky Equine Research Incorporated   (United States)

Author keywords

Carbohydrate oxidation; Catecholamines; Glucagon; Insulin; Propranolol; Stable isotopes

Indexed keywords

ADRENALIN; CARBOHYDRATE; FATTY ACID; GLUCAGON; GLUCOSE; NORADRENALIN; PROPRANOLOL;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; EXERCISE; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; HORSE; NONHUMAN; PRIORITY JOURNAL; WORKLOAD;

EID: 0034495867     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2000.89.3.1086     Document Type: Article

References (59)

1. Effect of β-receptor blockade on splanchnic and muscle metabolism during prolonged exercise in men
2. Biochemical and physiological effects of catecholamine administration in the horse
3. Limiting factors for maximum oxygen uptake and determinants of endurance performance
4. Carbohydrate metabolism during exercise: Influence of circulating fat availability
5. Effect of β-adrenergic blockade on response to exercise in sedentary and active subjects
6. Effect of β-adrenoceptor blockade on heart rate, hepatic blood flow and circulating noradrenaline during exercise in man
7. Effect of a selective rise in sinusoidal norepinephrine on HGP is due to an increase in glycogenolysis
8. 2 peak in untrained humans
9. Endurance training decreases plasma glucose turnover and oxidation during moderate-intensity exercise in men
10. Sympathetic drive to liver and nonhepatic splanchnic tissues during heavy exercise
11. Role of hepatic α- and β-adrenergic receptor stimulation on hepatic glucose production during heavy exercise
12. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise
13. Energetics and performance
14. 2 measuring systems
15. Calculation of substrate oxidation rates in vivo from gaseous exchange
16. Hormonal and Metabolic Adaptation to Exercise. New York: Thieme
17. Glucagon and plasma catecholamines during β-receptor blockade in exercising man
18. Glucose infusion attenuates endogenous glucose production and enhances glucose use of horses during exercise
19. Epinephrine translocates GLUT-4 but inhibits insulin-stimulated glucose transport in rat muscle
20. Effect of increased plasma free fatty acid concentrations on muscle metabolism in exercising men
21. Glucose kinetics during prolonged exercise in trained men
22. Effect of furosemide and weight carriage on energetic responses of horses to incremental exertion
23. Dissipation of metabolic heat in the horse during exercise
24. Respiratory and metabolic responses in the horse during moderate and heavy exercise
25. Glucose production during strenuous exercise in humans: Role of epinephrine
26. Effect of adrenaline on glucose kinetics during exercise in adrenalectomised humans
27. Role of β-adrenergic receptors in mobilization of energy sources in exercising dogs
28. Effect of epinephrine on carbohydrate metabolism in exercising dogs
29. Regulation of glucose utilization in human skeletal muscle during moderate dynamic exercise
30. Regulation of hepatic glucose production during exercise in humans: Role of sympathoadrenergic activity
31. Glucose homeostasis during exercise in humans with a liver or kidney transplant
32. Influence of active muscle mass on glucose homeostasis
33. An improved technique for extracting catecholamines from body fluids
34. Factors contributing to increased muscle fatigue with β-blockers
35. Plasma epinephrine reduces blood glucose clearance during low-intensity exercise
36. Cardiorespiratory and metabolic effects of propranolol during maximal exercise
37. Validation of rapid solid-phase radioimmunoassay for canine, bovine, and equine insulin
38. Adrenergic mechanisms for the effects of epinephrine on glucose production and clearance in man
39. Altitude and β-blockade augment glucose utilization during submaximal exercise
40. Design of the oxygensubstrate pathways. II. Defining the upper limits of carbohydrate and fat oxidation
41. Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration
42. Hematology and biochemistry
43. Adrenergic modulation of pancreatic A, B, and D cells
44. Effects of propranolol on cardiopulmonary function in the pony during submaximal exercise
45. The roles of catecholamines in glucoregulatian in intense exercise as defined by islet cell clamp technique
46. Glucoregulation during and after intense exercise: Effects of β-blockade
47. Adrenergic blockade alters glucose kinetics during exercise in insulin-dependent diabetics
48. The actions of the β-adrenoreceptor blocking agents propranolol and metoprolol in the maximally exercised horse
49. Role of liver nerves and adrenal medulla in glucose turnover of running rats
50. Influences of glucose loading and of injected insulin on hepatic glucose output
51. The influence of propranolol on cardiovascular function in conscious and anaesthetized horses
52. β-Adrenoreceptor blockade and exercise. An update
53. Regulation of glucose fluxes during exercise in the postabsorptive state
54. Exercise-induced fall in insulin and hepatic carbohydrate metabolism during muscular work
55. Glucagan is a primary controller of hepatic glycogenolysis and gluconeogenesis during muscular work
56. Hepatic nerves are not essential to the increase in hepatic glucose production during muscular work
57. Design of the oxygensubstrate pathways. III. Partitioning of energy provision from carbohydrates
58. β-Blockade and lipolysis during endurance exercise