Modulation of recombinant T-type Ca2+ channels by hypoxia and glutathione

Pflugers Archiv European Journal of Physiology

Volumn 441, Issue 2-3, 2000, Pages 181-188

  Fearon, I M ^a   Randall, A D ^b   Perez Reyes, E ^c   Peers, C ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

1 subunits; Glutathione; Hypoxia; Inhibition; Redox; T type Ca2+ channels

Indexed keywords

CALCIUM CHANNEL T TYPE; CALCIUM ION; GLUTATHIONE; GLUTATHIONE DISULFIDE; PROTEIN SUBUNIT;

ARTICLE; CALCIUM CURRENT; ELECTRIC ACTIVITY; ELECTRIC POTENTIAL; HUMAN; HUMAN CELL; HYPOXIA; INHIBITION KINETICS; PRIORITY JOURNAL; STEADY STATE;

ANIMALS; CALCIUM CHANNELS, T-TYPE; CELL HYPOXIA; CELL LINE; ELECTRIC CONDUCTIVITY; EMBRYO; GENE EXPRESSION; GLUTATHIONE; HUMANS; KIDNEY; NICKEL; OXIDATION-REDUCTION; OXYGEN; RATS; RECOMBINANT PROTEINS;

EID: 0034494253     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240000424     Document Type: Article

References (37)

1. 2 sensing
2. 2 chemoreception
3. 2 sensor in rat pulmonary vasculature
4. Mechanisms of oscillatory activity in guinea pig nucleus reticularis thalami in vitro - A mammalian pacemaker
5. Potassium channel modulated by hypoxia and the redox status in glomus cells of the carotid body
6. Redox modulation of L-type calcium channels in ferret ventricular myocytes - Dual mechanism regulation by nitric oxide and s-nitrosothiols
7. Specific petitmal anticonvulsants reduce calcium currents in thalamic neurons
8. + channels
9. 2+ channel gene family
10. v3.1c, a T-type calcium channel from human brain
11. 2+ channel
12. 1C subunits by redox agents and hypoxia
13. Differential oxygen sensitivity of calcium channels in rabbit smooth muscle cells of conduit and resistance pulmonary-arteries
14. 2 inhibits calcium channel activity in arterial smooth muscle cells
15. Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation
16. Low threshold calcium spikes, intrinsic neuronal oscillation and rhythm generation in the CNS
17. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
18. Intrathalamic rhythmicity studied in vitro: Nominal T-current modulation causes robust antioscillatory effects
19. Effect of sulfhydryl oxidation on ionic and gating currents associated with L-type calcium channels in isolated guinea pig ventricular myocytes
20. Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family
21. Nickel block of three cloned T-type calcium channels: Low concentrations selectively block α1H
22. + channels in small pulmonary arterial smooth muscle cells of the rabbit
23. Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurons in vitro
24. 2 in typed chemoreceptor cells
25. 2+ channels by the neuroprotective agent BW619C89 (Sipatrigine)
26. Hypoxia-induced catecholamine secretion in isolated new-born rat adrenal chromarlin cells is mimicked by inhibition of mitochondrial respiration
27. Oxygen sensing by ion channels and chemotransduction in single glomus cells
28. Redox agents as a link between hypoxia and the responses of ionic channels in rabbit pulmonary vascular smooth muscle
29. Oxygen-sensitive ion channels
30. 2 sensitivity to Kv4.2 hut not to Shaker channels
31. Molecular characterization of a neuronal low-voltage-activated T-type calcium channel
32. Calcium currents in respiratory neurons of the cat in vivo
33. Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels
34. Hypoxic enhancement of quantal catecholamine secretion - Evidence for the involvement of amyloid beta-peptides
35. The mechanism of acute hypoxic pulmonary vasoconstriction the - Tale of 2 channels
36. 2+ conductances in pulmonary artery cells
37. + channels in rat pulmonary artery smooth muscle cells