The effects of various factors on the release rate of a poorly soluble drug (carbamazepine) from hydroxypropyl methylcellulose matrices

S.T.P. Pharma Sciences

Volumn 10, Issue 6, 2000, Pages 473-478

  Akbari, J ^a   Adrangui, M ^a   Farid, Dj ^a   Siahi Shadbad, M R ^a   Saeedi, M ^a   Nokhodchi, A ^a  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Compression pressure; Hydroxypropyl methylcellulose matrices; Kinetics of release; Particle size; Release rate; Surfactants

Indexed keywords

CARBAMAZEPINE; HYDROXYPROPYLMETHYLCELLULOSE; POLYSORBATE; SURFACTANT;

ARTICLE; COMPRESSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; PARTICLE SIZE;

EID: 0034492822     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Pharmacokinetics of carbamazepine in normal man
2. Doubled-blind comparison of conventional and controlled-release carbamazepine in health subjects
3. Swelling of hydroxypropylmethyl cellulose matrix tablet. Part 1. Characterization of swelling using a novel optical imaging method
4. Prediction of polymer dissolution in swellable controlled release systems
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8. Binding of surfactants by polymers
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12. Some factors affecting the release of a water soluble drug from a compressed hydrophilic matrix
13. Dissolution of a poorly water soluble drug, indomethacin, from hydroxypropylmethylcellulose controlled release tablets
14. Evaluation of solubilizers in the drug release testing of hydrophilic matrix extended release tablets of felodipine
15. Review of cellulose ethers in hydrophilic matrices for oral controlled release dosage forms
16. Use of thermodynamic activation parameters and compression analysis to model drug release from hydrophobic matrices
17. Interaction of anionic surfactants with a non-ionic cellulose ethers in solution and in the gel state by pulsed field gradient NMR