Role of DNA minor groove alkylation and DNA cross-linking in the cytotoxicity of polybenzamide mustards

Anti-Cancer Drug Design

Volumn 15, Issue 4, 2000, Pages 245-253

  Turner, P R ^a   Denny, W A ^a   Ferguson, L R ^a  

^a THE UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Cross link; Cytotoxicity; Minor groove alkylator; Mustard; Polybenzamide

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ADENINE; BENZAMIDE DERIVATIVE; CHLORAMBUCIL; CHLORMETHINE; DNA POLYMERASE; POLYBENZAMIDE MUSTARD; TAQ POLYMERASE; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SEQUENCE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL REGENERATION; CONFORMATIONAL TRANSITION; CROSS LINKING; CYTOTOXICITY; DNA ADDUCT; DNA ALKYLATION; DNA CROSS LINKING; DNA SEQUENCE; DNA STRAND; PRIORITY JOURNAL; PROTEIN INTERACTION;

ADENINE; ALKYLATION; ANTINEOPLASTIC AGENTS, ALKYLATING; BENZAMIDES; BISBENZIMIDE; CHLORAMBUCIL; CROSS-LINKING REAGENTS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FLUORESCENT DYES; NITROGEN MUSTARD COMPOUNDS; NUCLEIC ACID CONFORMATION; TAQ POLYMERASE;

BRASSICACEAE;

EID: 0034488024     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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