Strong association of HLA-B27 heavy chain with β2-microglobulin

Human Immunology

Volumn 61, Issue 12, 2000, Pages 1197-1201

  Tran, Tri Minh ^a,c   Hořejší, Václav ^b   Weinreich, Stephanie ^d   Pla, Marika ^e   Breur, Brigitta S ^d   Čapková, Jana ^b   Flieger, Miroslav ^c   Ivanyi, Pavol ^a   Ivašková, Eva ^a  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^d CENTRAL LABORATORY   (Netherlands)

^e SAINT LOUIS HOSPITAL   (France)

Author keywords

2 microglobulin; HLA antigens; Monoclonal antibody; Western blotting

Indexed keywords

BETA 2 MICROGLOBULIN; EPITOPE; HLA ANTIGEN CLASS 1; HLA B27 ANTIGEN; HLA B7 ANTIGEN; MONOCLONAL ANTIBODY;

ANTIGEN DETECTION; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DENATURATION; DISSOCIATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN INTERACTION;

ANIMALS; ANTIBODIES, MONOCLONAL; BETA 2-MICROGLOBULIN; BLOTTING, WESTERN; CELL LINE; CELL LINE, TRANSFORMED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HLA-B27 ANTIGEN; HUMANS; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR WEIGHT; SODIUM DODECYL SULFATE;

EID: 0034486402     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(00)00220-2     Document Type: Article

References (13)

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9. Crosses of two independently derived transgenic mice demonstrate functional complementation of the genes encoding heavy (HLA-B27) and light (beta-2-microglobulin) chain of HLA class I antigens
10. Serological prescreening data analysis book
11. The beta-2-microglobulin dissociation rate is an accurate measure of the stability of MHC class I heterotrimers and depends on which peptide is bound
12. Structural features of MHC class I molecules that might facilitate alternative pathways of presentation
13. HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure