Advanced testing of granule friability determined from size distribution data

Pharmazeutische Industrie

Volumn 62, Issue 12, 2000, Pages 999-1002

  Airaksinen, S ^a   Antikainen, O ^a   Rantanen, J ^a   Yliruusi, J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Friability; Granulation; Sieve analysis

Indexed keywords

THEOPHYLLINE DERIVATIVE;

ARTICLE; DRUG GRANULATION; PARTICLE SIZE; STRENGTH; TABLET FRIABILITY;

EID: 0034486284     PISSN: 0031711X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Batch production of pharmaceutical granulations in a fluidized bed, I: Effects of process variables on physical properties of final granulation
2. Diffusion model for fluidized-bed drying
3. Attrition of theophylline granules during drying in a fluidized bed granulator
4. Granule growth kinetics and attrition of granules made of different materials in a fluidized bed granulator
5. Control of fluidized bed granulation, V. Factors affecting granule growth
6. Test methods for granulates
7. Compression characteristics of granulated materials, V. Mechanical properties of individual granules, assessed by diametral compression, in granulations with different volume reduction behaviour
8. Determination of pellet friability by use of an air stream apparatus
9. 3 factorial design and multilinear stepwise regression analysis in studying the fluidized bed granulation process, Part I
10. The effect of raw material and atomizing air pressure on the properties of granules prepared in a fluidized bed granulator
11. Control of fiuidized bed granulation, IV. Effects of binder solution and atomization on granule size and size distribution
12. The granulation and compression of powders
13. Next generation fluidized bed granulator automation