Internal motional amplitudes and correlated bond rotations in an α-helical peptide derived from 13C and 15N NMR relaxation

Protein Science

Volumn 9, Issue 11, 2000, Pages 2118-2127

  Idiyatullin, Djaudat ^a   Krushelnitsky, Alexei ^a   Nesmelova, Irina ^a   Daragan, Vladimir A ^a   Mayo, Kevin H ^a   Blanco, Francesco ^b   Serrano, Luis ^b  

^a University of Minnesota   (United States)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

13C and 15N relaxation; Anisotropic tumbling; Correlated motions; Molecular dynamics; NMR; Peptide; Trifluoroethanol; helix

Indexed keywords

AMINO ACID DERIVATIVE; CARBON; CARBON 13; GLYCYLPHENYLALANYLSERYLLYSYLALANYLGLUTAMINYLLEUCYLALANYLLYSYLALANYLARGINYLA LANYLALANYLLYSYLARGINYLGLYCYLGLYCYLTYROSINE; HYDROGEN; NITROGEN 15; PEPTIDE; TRIFLUOROETHANOL; UNCLASSIFIED DRUG; WATER;

ALPHA HELIX; AMPLITUDE MODULATION; ANISOTROPY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; MOTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STABILITY;

AMINO ACID SEQUENCE; ANISOTROPY; CARBON; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; NITROGEN; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTONS; TEMPERATURE; THERMODYNAMICS; TRIFLUOROETHANOL; WATER;

BIKINIA LE-TESTUI;

EID: 0034486194     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.9.11.2118     Document Type: Article

References (26)

1. NMR order parameters of biomolecules: A new analytical representation and application to the Gaussian axial fluctuation model
2. Trifluoroethanol and colleagues: Cosolvents come of age. Recent studies with peptides and proteins
3. Backbone and side chain dynamics of residues in a partially folded β-sheet peptide from PF4
4. α methylenes in a GXX-repeat hexadecapeptide
5. 13C NMR multiplet relaxation data from peptides and proteins
6. 15N NMR relaxation data
7. 13C NMR relaxation of alanine-methyl side chain motions in peptides
8. 15N NMR relaxation
9. 13C-NMR relaxation data
10. Using the model free approach to analyze NMR relaxation data in cases of anisotropic molecular diffusion
11. 15N NMR relaxation
12. Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. I. Theory and range of validity
13. Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. II. Analysis of experimental results
14. Spin-lattice relaxation measurements in slowly relaxing complex spectra
15. 13C-multiplet NMR relaxation-derived ring puckering and backbone dynamics in proline-containing glycine-based peptides
16. 13C-NMR relaxation measurements
17. The hydrophobic-staple motif and a role for loop-residues in α-helix stability and protein folding
18. Investigation of protein motions via relaxation measurements
19. 13C-NMR relaxation
20. Computer-optimized decoupling scheme for wideband applications and low-level operation
21. An improved sequence for broadband decoupling: WALTZ-16
22. Spin diffusion measurements: Spin echoes in the presence of a time dependent field gradient
23. xsystems
24. Intramolecular dipolar relaxation in multi-spin systems
25. Dynamics of aromatic amino acid residues in BPTI