Induction of estradiol synthesis by probucol in the adenocarcinoma cells of an ovarian clear cell tumor

Anticancer Research

Volumn 20, Issue 6 B, 2000, Pages 4397-4401

  Honda, K I ^a   Ishiko, O ^a   Wakasa, K ^a   Sumi, T ^a   Kawamura, N ^a   Ogita, S ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

Adenocarcinoma; Clear cell tumor; Estradiol; Ovary; Probucol

Indexed keywords

ANTIOXIDANT; ESTRADIOL; ESTROGEN; ESTRONE; LOW DENSITY LIPOPROTEIN RECEPTOR; PROBUCOL;

ADENOCARCINOMA; ARTICLE; CLEAR CELL CARCINOMA; CONTROLLED STUDY; CYTOCHEMISTRY; CYTOLOGY; ENDOPLASMIC RETICULUM; ESTROGEN SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MITOCHONDRION; MUELLERIAN DUCT; OVARY TUMOR; PRIORITY JOURNAL; RIBOSOME; STEROID HYDROXYLATION; TUMOR CELL CULTURE;

ADENOCARCINOMA, CLEAR CELL; ANTICHOLESTEREMIC AGENTS; ANTIOXIDANTS; ESTRADIOL; ESTRONE; FEMALE; HUMANS; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; PROBUCOL; RECEPTORS, LDL;

EID: 0034482495     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Evidence for an additional intracellular site of action of probucol in the prevention of oxidative modification of low density lipoprotein
2. Probucol prevents oxidative injury to endothelial cells
3. Ameliorative effect of dietary probucol on polychlorinated biphenyls-induced hypercholesterolemia and lipid peroxidation in the rat
4. Hormone secretion of krukenberg tumors
5. Oestrogenic activity associated with non-feminizing ovarian tumors after the menopause
6. Histochemical demonstration of 3β-and 17β-hydroxysteroid dehydrogenase activities in porcine ovary
7. Mesonephroma ovarii (hypernephroid carcinoma)
8. Ultrastructure and histogenesis of clear cell carcinoma of the ovary
9. Clear cell carcinoma of the vagina
10. Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia
11. 3,5-Di-t-4-hydroxytoluene (BHT) and probucol stimulate selectively the reaction of mammalian 15-1ipoxygenase with biomembranes
12. Ovarian clear-cell carcinoma producing estradiol and human chorionic gonadotropin
13. In vitro inhibition by estrogens of the oxidative modifications of human lipoproteins
14. Characterization of the steroid binding site: A method to evaluate stereospecificity of hydrogen transfer by steroid dehydrogenases