Influence of proliferation, differentiation and dedifferentiation factors on the expression of the lysosomal cysteine proteinase cathepsin L (CL) in thyroid cancer cell lines

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 487-495

  Plehn, A ^a   Gunther D ^a   Aurich, H ^a   Hoang Vu, C ^a   Weber, E ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN L; CYSTEINE PROTEINASE;

CANCER CELL CULTURE; CANCER INVASION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONFERENCE PAPER; ENZYME ACTIVITY; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROTEIN SECRETION; THYROID CANCER;

ADENOCARCINOMA, FOLLICULAR; CARCINOMA; CATHEPSINS; CELL DIFFERENTIATION; CELL DIVISION; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; ENZYME INDUCTION; ENZYME PRECURSORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIDERMAL GROWTH FACTOR; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INSULIN; LYSOSOMES; NEOPLASM PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; THYROID NEOPLASMS; THYROTROPIN; TUMOR CELLS, CULTURED;

EID: 0034473276     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (17)

1. Expression of cathepsin L in human tumors
2. Receptors and receptor-transducing systems in normal and neoplastic human thyroid tissue
3. Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts
4. Procathepsin L, a proteinase that cleaves human C3, the third component of complement, confers high tumorigenic and metastatic properties to human melanoma cells
5. Growth regulation of human thyrocytes by thyrotropin, cyclic adenosine monophosphate, epidermal growth factor and insulin-like growth factor
6. Cathepsin L and cancer
7. Secretion of a latent, acid activatable cathepsin L precursor by human non-small lung cancer cell line
8. Purification, characterization, and cDNA cloning of procathespin L from the culture medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina (flesh fly), and its involvement in the differentiation of imaginal discs
9. A cysteine proteinase, which cleaves human C3, the third component of complement, is involved in tumorigenicity and metastasis of human melanoma
10. Proenzyme form of cathepsin L produced by thymic epithelial cells promotes proliferation of immature thymocytes in the presence of IL-1, IL-7, and anti-CD3 antibody
11. Individually different proliferation responses of differentiated thyroid carcinomas to thyrotropin
12. Importance and variability of transducing systems in the control of thyroid cell function, proliferation and differentiation
13. Influence of thyroid-stimulating hormone, epidermal growth factor, and insulin-like growth factor I on growth of thyroid cells in vitro
14. Expression and immunohistochemical localization of cathepsin L during the progression of human gliomas
15. Monoclonal antibodies against cathepsin L and procathepsin L of different species
16. Hybridoma cells producing antibodies to cathepsin L have greatly reduced potential für tumor growth
17. Suppression by cathepsin L inhibitors of the invasion of amnion membranes by murine cancer cells