Matrix metalloproteinases (MMP-8, -13, and -14) interact with the clotting system and degrade fibrinogen and factor XII (Hagemann factor)

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 217-228

  Tschesche, Harald ^a   Lichte, Andrea ^a   Hiller, Oliver ^a   Oberpichler, Andre ^a   Büttner, Frank H ^b   Bartnik, Eckart ^b  

^a BIELEFELD UNIVERSITY   (Germany)

^b SANOFI   (France)

Author keywords

Clotting; Degradation; Factor XII (Hagemann factor); Fibrinogen; Matrix metalloproteinases

Indexed keywords

BLOOD CLOTTING FACTOR 12; COLLAGENASE 3; FIBRINOGEN; FIBRONECTIN; KALLIKREIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; NEUTROPHIL COLLAGENASE; UNCLASSIFIED DRUG;

BLOOD CLOTTING; CATALYSIS; CONFERENCE PAPER; ENZYME ACTIVITY; FIBRINOGEN METABOLISM; HEMOSTASIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

CATALYTIC DOMAIN; COLLAGENASES; ENZYME ACTIVATION; FACTOR XII; FIBRINOLYSIS; HUMANS; HYDROLYSIS; KALLIKREINS; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 8; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; THROMBIN;

EID: 0034473090     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding
2. Matrix metalloproteinases and timps: Properties and implications for the rheumatic diseases
3. Changing views of the role of matrix metalloproteinases in metastasis
4. Recognition of distinct adhesive sites on fibrinogen by related integrins or platelets and endothelial cells
5. Matrix metalloproteinases and the development of cancer
6. 3 mediated melanoma cell adhesion to fibrinogen and its plasmic fragments
7. Amino acid sequence of human β-factor XIIa
8. Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
9. Structural basis of the activation and action of trypsin
10. Matrix metalloproteinases
11. Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts
12. Amino acid sequence of the heavy chain of human ∀-factor XIIa (Activated Hagemann Factor)
13. Matrix metalloproteinases
14. New concepts in coagulation
15. Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2
16. Mechanism of cell surface activation of 72 kDa type IV collagenase
17. Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2
18. Matrix metalloproteinases and their inhibitors in connective tissue remodeling
19. Matrix metalloproteinases and diseases of the CNS
20. Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor. Membrane type 1-matrix metalloproteinase 1 (MT1-MMP)