Molecular tools for the study of titin's differential expression

Advances in Experimental Medicine and Biology

Volumn 481, Issue , 2000, Pages 35-52

  Centner, T ^a   Fougerousse, F ^a   Freiburg, A ^a   Witt, C ^a   Beckmann, J S ^a   Granzier, H ^a   Trombitas K ^a   Gregorio, C C ^a   Labeit, S ^a   Greaser, ^a   Bullard, ^a   Linke, ^a   Pollack, ^a   Trinick, ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIN; PROTEIN ANTIBODY;

CONFERENCE PAPER; ELASTICITY; GENE LOCUS; GENOME; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SKELETAL MUSCLE;

VERTEBRATA;

EID: 0034471816     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-4267-4_3     Document Type: Conference Paper

References (44)

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3. Identification and characterization of two huge protein components of the brush border cytoskeleton: Evidence for a cellular isoform of titin
4. Myofilament-generated tension oscillations during partial calcium activation and activation dependence of the sarcomere length-tension relation of skinned cardiac cells
5. The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: A map of ten nonrepetitive epitopes starting at the Z line extends close to the M line
6. Titin antibodies in myasthenia gravis: Identification of a major autoimmunogenic region of titin
7. A molecular map of titin/connectin elasticity reveals two different mechanisms acting in series
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9. Passive tension in cardiac muscle: Contribution of collagen, titin, microtubules and intermediate filaments
10. The N terminal of titin spans the Z-Disk. Its interaction with a novel 19 kDa ligand (T-cap) is required for sarcomeric integrity
11. Muscle assembly: A titanic achievement?
12. Mechanically driven contour-length adjustment in rat cardiac titin's unique N2B sequence
13. Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing
14. Independent assembly of 1.6 μm long bipolar MHC filaments and 1-Z-I bodies
15. A physiological role for titin and nebulin in skeletal muscle
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18. Genomic organization of the M-line titin and its tissue-specific expression in two distinct isoforms
19. Titins, giant proteins in charge of muscle ultrastructure and elasticity
20. Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography
21. A spring tale: New facts on titin elasticity
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23. Nature of PEVK-titin elasticity in skeletal muscle
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25. Human autoantibodies reveal titin as a chromosomal protein
26. Connectin, an elastic protein of muscle: Characterization and function
27. Connectin/titin, giant elastic protein of muscle
28. Characterization of nebulette and nebulin and emerging concepts of their roles for vertebrate Z-disks
29. Two immnunoglobulin-like domains of the Z-disk portion of titin interact in a conformation-dependent way with telethonin
30. Molecular structure of the sarcomeric M band: Mapping of titin andmyosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin
31. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
32. Architecture and function in the muscle sarcomere
33. Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence
34. Tissue-specific expression and α-actinin binding properties of the Z disk titin. Implications for the nature of vertebrate Z disks
35. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
36. Titin as a scaffold and spring. Cytoskeleton
37. Titin extensibility in situ: Entropic elasticity of permanently folded and permanently unfolded molecular segments
38. Telethonin, a novel sarcomeric protein of heart and skeletal muscle
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40. Titin/connectin and nebulin: Giant protein rulers of muscle structure and function
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42. Does titin regulate the length of muscle thick filaments?
43. A survey of the primary structure and the interspecies conservation of I-band titin's elastic elements in vertebrates
44. Molecular structure of the sarcomeric z-disk: Two types of titin interactions lead to an asymmetrical sorting of alpha-actinin