MYCN oncogene and angiogenesis: Down-regulation of endothelial growth inhibitors in human neuroblastoma cells: Purification, structural, and functional characterization

Advances in Experimental Medicine and Biology

Volumn 476, Issue , 2000, Pages 239-248

  Hatzi, Elissavet ^a   Breit, Stephen ^b   Zoephel, Andreas ^c   Ashman, Keith ^d   Tontsch, Ulrike ^c   Ahorn, Horst ^c   Murphy, Carol ^a   Schweigerer, Lothar ^b   Fotsis, Theodore ^a  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c Boehinger Ingelheim R + D Vienna   (Australia)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Activn A; Angiogenesis; Endothelial cell; Inhibitors; Malignant transformation; MYCN; Neuroblastoma; Oncogene

Indexed keywords

ACTIVIN A;

AMINO ACID SEQUENCE; ANGIOGENESIS; CELL PROLIFERATION; CONFERENCE PAPER; DOWN REGULATION; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; MALIGNANT TRANSFORMATION; NEUROBLASTOMA CELL; ONCOGENE MYC; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTEIN STRUCTURE; TUMOR GROWTH;

ACTIVINS; AMINO ACID SEQUENCE; ANGIOGENESIS INHIBITORS; CELL DIVISION; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; INHIBINS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NEOVASCULARIZATION, PATHOLOGIC; NEUROBLASTOMA; ONCOGENES; PROTO-ONCOGENE PROTEINS C-MYC; TUMOR CELLS, CULTURED;

EID: 0034471618     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: 10.1007/978-1-4615-4221-6_19     Document Type: Article

References (18)

1. Angiogenesis
2. Relation of vascular proliferation to tumor growth
3. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
4. Angiogenesis in cancer, vascular, rheumatoid and other disease
5. Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
6. The multistep nature of cancer
7. The molecular genetics of cancer
8. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
9. The modulation of thrompospondin and other naturally occuring inhibitors of angiogenesis during tumor progression
10. Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells
11. How tumors become angiogenic
12. Amplification of MYCN in untreated human neuroblastomas correlates with advanced disease stage
13. Detection of NMYC oncogene expression in human neuroblastoma by in situ hybridization and blot analysis: Relationship to clinical outcome
14. Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma
15. Augmented MYCN expression advances the malignant phenotype of human neuroblastoma cells: Evidence for induction of autocrine growth activity
16. Down-regulation of endothelial cell growth inhibitors by enhanced MYCN oncogene expression in human neumblastoma cells
17. Human activin A gene
18. The N-myc oncoprotein is associated in vivo with the phosphoprotein Max (p20/22) in human neumblastoma cells