Specific inhibitors of dipeptidyl peptidase IV suppress mRNA expression of DP IV/CD26 and cytokines

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 139-143

  Arndt, M ^a   Reinhold, D ^a   Lendeckel, U ^a   Spiess, A ^a   Faust, J ^a   Neubert, K ^a   Ansorge, S ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Cytokines; Dipeptidyl peptidase IV (DP IV, CD26); PBMC; Quantitative RT PCR

Indexed keywords

CYTOKINE; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENZYME INHIBITOR; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; MESSENGER RNA; POKEWEED MITOGEN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

CELL CYCLE G1 PHASE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD26; AUTOCRINE COMMUNICATION; ENZYME INDUCTION; FEEDBACK; G1 PHASE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYSINE; POKEWEED MITOGENS; RNA, MESSENGER; SERINE PROTEINASE INHIBITORS; T-LYMPHOCYTES; THIAZOLES; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

PHYTOLACCACEAE;

EID: 0034471583     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (13)

1. Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene
2. Membrane-bound peptidases of lymphocytes: Functional implications
3. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
4. Functional role of CD26 on human B lymphocytes
5. Expression and functional role of dipeptidyl peptidase IV (CD26) on human natural killer cells
6. A rapid method for the isolation of functional thymus-derived routine lymphocytes
7. Dipeptidyl peptidase IV: A cell surface peptidase involved in regulating T cell growth
8. Extended investigation of the substrate specificity of dipeptidyl peptidase IV from pig kidney
9. Inhibitors of dipeptidyl peptidase IV induce secretion of transforming growth factor-beta 1 in PWM-stimulated PBMC and T cells
10. Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-β1 (TGF-β1) in stimulated mouse splenocytes and thymocytes
11. The dipeptidyl peptidase IV, a membrane enzyme involved in the proliferation of T lymphocytes
12. CD26 antigen is a surface dipeptidyl peptidase IV (DPPIV) as characterized by monoclonal antibodies clone TII-19-4-7 and 4EL1C7