Enzymatic activity is not a precondition for the intracellular calcium increase mediated by mAbs specific for aminopeptidase N/CD13

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 43-47

  Santos, A N ^a   Langner, J ^a   Riemann, D ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Aminopeptidase N; CD13; Inhibitors; Intracellular calcium

Indexed keywords

ACTINONIN; BESTATIN; MICROSOMAL AMINOPEPTIDASE; MONOCLONAL ANTIBODY; PROBESTIN;

CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD13; CALCIUM; CALCIUM SIGNALING; HUMANS; HYDROXAMIC ACIDS; ION TRANSPORT; LEUCINE; NEOPLASM PROTEINS; OLIGOPEPTIDES; PROTEASE INHIBITORS; U937 CELLS;

EID: 0034470221     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (5)

1. 2+ indicators with greatly improbed fluorescence properties
2. Role of alanyl aminopeptidase in growth and function of human T cells
3. Binding of antibodies to different CD13 epitopes on human myeloid leukaemic cell
4. Inhibition of Aminopeptidase N, A and W. A reevaluation of the action of bestatin and inhibitors of angiotensin converting enzyme