Transurethral alprostadil for the treatment of erectile dysfunction: Results of a multicentre trial

Annals of the Academy of Medicine Singapore

Volumn 29, Issue 6, 2000, Pages 727-731

  Li, M K ^a,b   Lim, P H C ^c   Wong, M Y C ^d   Fok, A ^e   Chia, S J ^f   Consigliere, D ^f   Adaikan, P G ^b   Moorthy, P ^c  

^a Urological Association of Singapore   (Singapore)

^b NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^c CHANGI GENERAL HOSPITAL   (Singapore)

^d Department of Urology ^*

^e SINGAPORE GENERAL HOSPITAL   (Singapore)

^f TAN TOCK SENG HOSPITAL   (Singapore)

Author keywords

Penile erection; Urethral suppository

Indexed keywords

PROSTAGLANDIN E1;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ERECTILE DYSFUNCTION; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PENIS ERECTION; SEXUAL INTERCOURSE; TREATMENT OUTCOME; URETHRA;

EID: 0034470184     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Kaiser F E. Erectile dysfunction in the aging man. In: Kaiser F E, editor. The Medical Clinics of North America: The Aging Male Patient. Philadelphia: WB Saunders Company, 1999; 83:1267-78.
2. Morley J E, Perry III H M. Androgen deficiency in aging men. In: Kaiser F E, editor. The Medical Clinics of North America: The Aging Male Patient. Philadelphia: WB Saunders Company, 1999; 83:1279-90.
3. Feldman H A, Goldstein I, Hatzichristou D G, Krane R J, MCKinlay J B. Impotence and its medical and psychosocial correlates: results of the ssachusetts Male Aging Study. J Urol 1994; 151:54-61.
4. Morley K E, Kaiser F E. Impotence of the internist's approach to diagnosis and treatment. Adv Intern Med 1993; 38:151-68.
5. NIH Consensus Development Panel on Impotence. JAMA 1993; 270:83-90.
6. Lim P H C, Ng F C. Erectile dysfunction in Singaporean men: presentation, diagnosis, treatment and results. Ann Acad Med Singapore 1992;21:248-53.
7. Goldstein I, Lue T F, Padma-Nathan H, Rosen R C, Steers W D, Wicker P A. Oral sildenafil in the treatment of erectile dysfunction. N Engl J Med 1998; 338:1397-404.
8. Brindley C S. Cavemosal alpha blockade: a new technique for investigating and treating erectile impotence. B J Psych 1983; 143: 332-37.
9. Virag R. Intracavernous injection of papaverine for erectile failure. Lancet 1982; 2:938.
10. Engel J D, McVary K T. Transurethral alprostadil as therapy for patients who withdrew from or failed prior intracavernous injection therapy. Urology 1998; 51:687-92.
11. Padma-Nathan H, Hellstrom W J, Kaiser F E, Labasky R, Lue T F, Nolten W E, et al. Treatment of men with erectile dysfunction with transurethral alprostadil. N Engl J Med 1997; 336:1-7.
12. Williams G, Abbou C C, Amar E T, Desvaux P, Flam T A, Lycklama G A B, et al. Efficacy and safety of transurethral alprostadil therapy in men th erectile dysfunction. Br J Urol 1998; 81:889-94.
13. Church P. The Medical Forum. Impotence, Part 1. Evaluation. Harvard Medical School Health Letter, 1989.
14. Karim S M M, Hiller K. Physiological roles and pharmacological actions of prostaglandins in relation to human reproduction. In: Karim S M M, editor. Prostaglandins and reproduction. Lancaster: MTP Press, 1975:23-75.
15. 1 in human penile erection. 2nd World Meeting on Impotence; 1986 June 16-20; Prague. Czeckoslovakia, 1986:26.
16. 1 on penile erection and failure. J Urol 1987; 137:1010.
17. Krane R J, Goldstein I, Saenz de Tejada I. Impotence. N Engl J Med 1989; 321:1648-59.
18. Roy A C, Adaikan P G, Sen D K, Ratnam S S. Prostaglandin 1-5 hydroxydehydrogenase activity in human penile corporal cavernosa and its significance in prostaglandin mediated penile erection. BrJ Urol 1989; 64:180-2.
19. Palmer L S, Valcic M, Melman A, Giraldi A, Wagner G, Christ G J. Characterization of cyclic AMP accumulation in cultured human corpus cavernosum smooth muscle cells. J Urol 1994; 152:1308-14.
20. Van Ahlen H, Peskar B A, Sticht G, Hertfelder H J. Pharmacokinetics of vasoactive substances administered into the human corpus cavernosum. J Urol 1994; 151:1227-30.