Current controlled trials: An opportunity to help improve the quality of clinical research

Current Controlled Trials in Cardiovascular Medicine

Volumn 1, Issue 1, 2000, Pages 3-8

  Chalmers, I ^a  

^a UK COCHRANE CENTRE   (United Kingdom)

Author keywords

Controlled clinical trials; Electronic publishing; Preprints; Publication bias; Quality of clinical research; Surrogate outcomes; Systematic reviews; Trial registration

Indexed keywords

CLINICAL RESEARCH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ELECTRONICS; HUMAN; MEDICAL LITERATURE; METHODOLOGY; NOTE; PUBLICATION; PUBLISHING; QUALITY CONTROL; REGISTRATION;

EID: 0034467941     PISSN: 14686708     EISSN: None     Source Type: Journal    
DOI: 10.1186/CVM-1-1-003     Document Type: Note

References (46)

1. The scandal of poor medical research
2. Salutary lessons from the Collaborative Eclampsia Trial
3. Which anticonvulsant for women with eclampsia? Evidence from the collaborative eclampsia trial
4. Real promises, unreal expectations
5. E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: A randomized controlled trial. E5 study investigators
6. Sorting out the doctor's bag
7. Surrogate end points, health outcomes, and the drug-approval process for the treatment of risk factors for cardiovascular disease
8. Effect of antiarrhythmic drugs on mortality after myocardial infarction
9. Effects of prophylactic antiarrhythmic drug therapy in acute myocardial infarction. An overview of results from randomized controlled trials
10. Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials
11. Meta-analytic evidence against prophylactic use of lidocaine in acute myocardial infarction
12. Discussion sections in reports of controlled trials published in general medical journals: Islands in search of continents?
13. The effect of lorcainide on arrhythmias and survival in patients with acute myocardial infarction
14. Bias, subjectivity, chance, and conflict of interest in editorial decisions
15. Academia and industry: Increasingly uneasy bedfellows
16. Is academic medicine for sale?
17. North and South: Bridging the information gap
18. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2
19. Clinical trial of indomethacin in Alzheimer's disease
20. Corticosteroids for acute traumatic brain injury (Cochrane Review)
21. Carotid endarterectomy for symptomatic carotid stenosis (Cochrane Review)
22. Brief psychological interventions ("debriefing") for trauma-related symptoms and the prevention of post traumatic stress disorder (Cochrane Review)
23. Publications and promotions for the clinical investigator
24. Clinical trials in cancer: The role of surrogate patients in defining what constitutes an ethically acceptable clinical experiment
25. How can medical journals help prevent poor medical research? Some opportunities presented by electronic publishing
26. Time to register randomised trials
27. Time to register randomised trials. The case is now unanswerable
28. Registering clinical trials
29. Being a modern pharmaceutical company: Involves making information available on clinical trial programmes
30. Safeguarding participants in clinical trials
31. Using systematically synthesised evidence to inform the funding of new clinical trials - The UK Medical Research Council approach
32. Denmark takes lead on research ethics
33. Electronic research archives for physics
34. Lancet electronic research archive in international health and eprint server
35. Netprints: The next phase in the evolution of biomedical publishing
36. Pardonable revisions and protocol reviews
37. Improving the conduct and reporting of clinical trials
38. Introduction
39. The international congress on peer review in biomedical publication
40. Improving the quality of reporting of randomized controlled trials: The CONSORT statement
41. Practical methodology of meta-analyses (overviews) using updated individual patient data
42. Ease-ing out of Tours
43. Unbiased, relevant, and reliable assessments in health care