Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism

Endocrinology

Volumn 141, Issue 2, 2000, Pages 846-849

  Emmen, J M A ^a   McLuskey, A ^a   Adham, I M ^a   Engel, W ^a   Verhoef Post, M ^a   Themmen, A P N ^a   Grootegoed, J A ^a   Brinkmann, A O ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYLSTILBESTROL; SOMATOMEDIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRYPTORCHISM; EMBRYO DEVELOPMENT; GENE DISRUPTION; GENE INACTIVATION; MESSENGER RNA SYNTHESIS; MOUSE; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROMOTER REGION; STEROIDOGENESIS; TESTIS CELL; TESTIS DEVELOPMENT;

ANIMALS; CRYPTORCHIDISM; DIETHYLSTILBESTROL; DNA-BINDING PROTEINS; FEMALE; FUSHI TARAZU TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; HOMEODOMAIN PROTEINS; HORMONES; INSULIN; LEYDIG CELLS; MALE; MICE; MICE, INBRED STRAINS; PREGNANCY; PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TESTIS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0034465666     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.141.2.846     Document Type: Article

References (29)

1. Transplacental hormonal carcinogenesis: Diethylstilbestrol as an example
2. A biphasic model for the hormonal control of testicular descent
3. Estrogen-induced cryptorchidism in animals
4. Development, structure and function of the cranial suspensory ligaments of the mammalian gonads in a cross-species perspective; Their possible role in effecting distrubed testicular descent
5. Anatomical and functional aspects of testicular descent and cryptorchidism
6. Inhibition, sous l'effect d'une hormone oestrogéne, du dèveloppement du gubernaculum du foetus mille de souris
7. Scanning electron microscopy shows inhibited gubernacular development in relation to undescended testes in oestrogen-treated mice
8. Biology of the relaxin-like factor (RLF)
9. The role of the testicular factor INSL3 in establishing the gonadal position
10. Mouse Leydig insulin-like (Ley I-L) gene: Structure and expression during testis and ovary development
11. Targeted disruption of the Insl3 gene causes bilateral cryptorchidism
12. Cryptorchidism in mice mutant for Insl3
13. A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation
14. Maternal oestrogen/xenoestrogen exposure alters expression of steroidogenic factor-1 (SF-1/Ad4BP) in the fetal rat testis
15. Transcription of the Leydig insulin-like gene is mediated by steroidogenic factor-1
16. Single-step method of RNA isolation by acid guanidinium thiocyanate- phenolchloroform extraction
17. A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the mullerian duct
18. Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I
19. Fetal development of Leydig cell activity in the mouse is independent of pituitary gonadotroph function
20. Gonadotropin-independent regulation of steroidogenesis in the fetal rat testis
21. Role of the fetal pituitary in cryptorchidism induced by exogenous maternal oestrogen during pregnancy in mice
22. Exogenous oestrogens prevent transabdominal testicular descent in mice with complete androgen resistance (testicular feminisation)
23. Testicular feminization: A model for testicular descent in mice and men
24. Both gonadotropin and testosterone fail to reverse estrogen-induced cryptorchidism in fetal mice: Furhter evidence for nonandrogenic control of testicular descent in the fetus
25. The hormonal control of testicular descent
26. Effect of prenatal exposure to diethylstilbestrol on Mullerian duct development in fetal male mice
27. Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3)
28. Relaxin-like factor: A highly specific and constitutive new marker for Leydig cells in the human testis
29. Are oestrogens involved in failing sperm counts and disorders of the male reproductive tract?